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The integrin family of cell adhesion receptors is emerging as a promising target of anticancer therapy. AlphaVbeta3 and alphaVbeta5 integrins are overexpressed on both glioma cells and tumor vasculature. Cilengitide, the most advanced specific integrin inh ...
Radiotherapy treatment planning requires exact delineation of tumors in acquired images. Further, motion and deformation of a tumor due to respiratory movements must be known in order to better target and dose the treatment radiation. Here we present and i ...
A high-resolution negative Calixarene resist has been used to pattern 2-nm-thick Ti O2 films on 50-nm-thick Pt layers by electron beam lithography, in order to carry out site controlled growth of Pb (Zr,Ti) O3 structures. Single dot structures have been wr ...
A focus/detector system of an X-ray apparatus and a method for generating projective or tomographic phase contrast recordings, are disclosed. In an embodiment of the system, the system includes a beam source equipped with a focus and a focus-side source gr ...
Reported MOSFET measurements concern mostly external radiotherapy and in vivo dosimetry. In this paper, we apply the technique for absolute dosimetry in the context of HDR brachytherapy using an 192Ir source. Measured radial dose rate distributions in wate ...
For radiotherapy treatment planning of retinoblastoma in childhood, Computed Tomography (CT) represents the standard method for tumor volume delineation, despite some inherent limitations. CT scan is very useful in providing information on physical density ...
Delineation of structures to irradiate (the tumors) as well as structures to be spared (e.g., optic nerve, brainstem, or eyes) is required for advanced radiotherapy techniques. Due to a lack of time and the number of patients to be treated these cannot alw ...
"Several cyclotron-based high intensity accelerators have been studied in the framework of the Energy Amplifier (EA) project proposed by Prof. C. Rubbia [1]. Among them, two basic designs are presented: a 380 MeV separated sector cyclotron delivering a hig ...
Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, t ...
This paper presents an ITK implementation for exporting the contours of the automated segmentation results to DICOM-RT Structure Set format. The “radiotherapy structure set” (RTSTRUCT) object of the DICOM standard is used for the transfer of patient struct ...