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How are listeners able to follow and enjoy complex pieces of music? Several theoretical frameworks suggest links between the process of listening and the formal structure of music, involving a division of the musical surface into structural units at multip ...
We develop theory and methodology for the problem of nonparametric registration of functional data that have been subjected to random deformation (warping) of their time scale. The separation of this phase variation ("horizontal" variation) from the amplit ...
This paper presents the historical development of the vertical extensions of unreinforced masonry buildings in the Eixample district of Barcelona and their impact on the seismic behaviour. Existing masonry buildings of Eixample present significant seismic ...
ABCG2 is an ATP-binding cassette (ABC) transporter whose function affects the pharmacokinetics of drugs and contributes to multidrug resistance of cancer cells. While its interaction with the endogenous substrate estrone-3-sulfate (E1S) has been elucidated ...
Viruses are genetically and structurally diverse, and outnumber cells by orders of magnitude. They can cause acute and chronic infections, suppress, or exacerbate immunity, or dysregulate survival and growth of cells. To identify chemical agents with pro- ...
Existing bridges in reinforced concrete (RC) need to be enhanced in order to comply with utilization and safety requirements of future use, in particular for higher traffic loads. Such enhancements comprise strengthening to increase the structural resistan ...
With the development of new materials and advanced structural analysis, alongside increasing aesthetic requirements, recent years have witnessed a trend toward longer, taller, and lighter footbridges. Different from vehicular bridges, footbridges carry rel ...
Innovations in statistical technology, in functions including credit-screening, have raised concerns about distributional impacts across categories such as race. Theoretically, distributional effects of better statistical technology can come from greater f ...
Optimal performance of civil infrastructure is an important aspect of liveable cities. A judicious combination of physics-based models with monitoring data in a validated methodology that accounts for uncertainties is explored in this paper. This methodolo ...
The human CC chemokine receptor 5 (CCR5) is a G protein-coupled receptor (GPCR) that plays a major role in inflammation and is involved in cancer, HIV, and COVID-19. Despite its importance as a drug target, the molecular activation mechanism of CCR5, i.e., ...