Concept
Thalassémie
Publications associées (18)
Inhibition of SRC-mediated integrin signaling in bone marrow niche enhances hematopoietic stem cell function
Interaction with microenvironmental factors is crucial for the regulation of hematopoietic stem cell (HSC) function. Stroma derived factor (SDF)-1 alpha supports HSCs in the quiescent state and is central to the homing of transplanted HSCs. Here, we show t ...
CELL PRESS2022Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort
Background: Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential ro ...
Biomed Central Ltd2013Three-dimensional organization of gene expression in erythroid cells
The history of globin research is marked by a series of contributions seminal to our understanding of the genome, its function, and its relation to disease. For example, based on studies on hemoglobinopathies, it was understood that gene expression can be ...
Elsevier2008