Neuropsychologie

Résumé

La neuropsychologie est une branche de la psychologie clinique qui s'intéresse aux relations entre le cerveau et le fonctionnement psychologique (fonctions cognitives, comportements et émotions) au moyen d'observations menées auprès de sujets normaux ou de patients présentant des lésions cérébrales d'origines diverses. Discipline neuroscientifique Discipline carrefour née principalement de l'interaction entre neurologie et psychologie, la neuropsychologie profite de l'engouement actuel pour les neurosciences et est aujourd'hui en plein essor. Pourtant ce n'est pas une discipline nouvelle : ses racines plongent dans l'Égypte ancienne où Imhotep établit le lien entre cerveau et sémiologie physique, et chez certains médecins de la Grèce antique comme Alcméon de Crotone ou Érasistrate qui défendent, contre l'école hippocratique, que le cerveau est l'organe de contrôle du corps et le siège de l'âme. Toutefois, pendant les ères romaine et chrétienne, le modèle de Galien, axé sur

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https://fr.wikipedia.org/wiki/Neuropsychologie

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Apraxia: a review

Aude Billard, Olaf Blanke, Biljana Petreska von Ritter-Zahony

Praxic functions are frequently altered following brain lesion, giving rise to apraxia - a complex pattern of impairments that is difficult to assess or interpret. In this chapter, we review the current taxonomies of apraxia and related cognitive and neuropsychological models. We also address the questions of the neuroanatomical correlates of apraxia, the relation between apraxia and aphasia and the analysis of apraxic errors. We provide a possible explanation for the difficulties encountered in investigating apraxia and also several approaches to overcome them, such as systematic investigation and modeling studies. Finally, we argue for a multidisciplinary approach. For example, apraxia should be studied in consideration with and could contribute to other fields such as normal motor control, neuroimaging and neurophysiology.

Elsevier2007

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This thesis presents possible computational mechanisms by which a humanoid robot can develop a coherent representation of the space within its reach (its peripersonal space), and use it to control its movements. Those mechanisms are inspired by current theories of peripersonal space representation and motor control in humans, targeting a cross-fertilization between robotics on one side, and cognitive science on the other side. This research addresses the issue of adaptivity the sensorimotor level, at the control level and at the level of simple task learning. First, this work considers the concept of body schema and suggests a computational translation of this concept, appropriate for controlling a humanoid robot. This model of the body schema is adaptive and evolves as a result of the robot sensory experience. It suggests new avenues for understanding various psychophysical and neuropsychological phenomenons of human peripersonal space representation such as adaptation to distorted vision and tool use, fake limbs experiments, body-part centered receptive fields, and multimodal neurons. Second, it is shown how the motor modality can be added to the body schema. The suggested controller is inspired by the dynamical system theory of motor control and allows the robot to simultaneously and robustly control its limbs in joint angles space and in end-effector location space. This amounts to controlling the robot in both proprioceptive and visual modalities. This multimodal control can benefit from the advantages offered by each modality and is better than traditional robotic controllers in several respects. It offers a simple and elegant solution to the singularity and joint limit avoidance problems and can be seen as a generalization of the Damped Least Square approach to robot control. The controller exhibits several properties of human reaching movements, such as quasi-straight hand paths and bell-shaped velocity profiles and non-equifinality. In a third step, the motor modalities is endowed with a statistical learning mechanism, based on Gaussian Mixture Models, that enables the humanoid to learn motor primitives from demonstrations. The robot is thus able to learn simple manipulation tasks and generalize them to various context, in a way that is robust to perturbations occurring during task execution. In addition to simulation results, the whole model has been implemented and validated on two humanoid robots, the Hoap3 and the iCub, enabling them to learn their arm and head geometries, perform reaching movements, adapt to unknown tools, and visual distortions, and learn simple manipulation tasks in a smooth, robust and adaptive way. Finally, this work hints at possible computational interpretations of the concepts of body schema, motor perception and motor primitives.

EPFL2009

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Depersonalization- and derealization-like phenomena of epileptic origin

Olaf Blanke, Nathaniel Evans, Lukas Heydrich

Objective Depersonalization refers to the sensation of being detached from one's body, often associated with feelings of loss of control over one's own body, actions, or thoughts. Derealization refers to the altered perception of one's surroundings that is experienced as unreal. Although usually reported by psychiatric patients suffering from depression or anxiety, single case reports and small case series have described depersonalization- and derealization-like symptoms in the context of epilepsy. Methods We investigated the brain mechanisms of ictal depersonalization- and derealization like symptoms by analyzing clinical and neuropsychological data as well as the epileptogenic zone based on a multimodal approach in a group of patients reporting depersonalization- (n = 9) and derealization-like symptoms (n = 7), from a single presurgical epilepsy center with focal epilepsy. We compared them with a group of control patients with experiential phenomena due to temporal lobe epilepsy (n = 28). Results We show that all patients with ictal depersonalization-like symptoms report altered self-identification with their body and mostly suffer from frontal lobe epilepsy with the epileptogenic zone in the dorsal premotor cortex, while patients with derealization-like symptoms suffer from temporal lobe epilepsy. This finding is supported by post-ictal neuropsychological deficits, showing that depersonalization-like symptoms were significantly more often associated with frontal lobe dysfunction as compared to the control patients and patients with derealization-like symptoms. Conclusion We argue that depersonalization of epileptic origin constitutes a distinct disorder due to frontal lobe epilepsy. We discuss these findings with respect to earlier accounts of depersonalization and the recent concept of bodily self-consciousness.

2019

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EPFL2009