Concept

Transduction de signal

Publications associées (1 000)

Chemical Biology Gateways to Mapping Location, Association, and Pathway Responsivity

Here we discuss, how by applying chemical concepts to biological problems, methods have been developed to map spatiotemporal regulation of proteins and small-molecule modulation of proteome signaling responses. We outline why chemical-biology platforms are ...

2019

MEMS Piezoelectric Accelerometer for Vibration Sensing in Harsh Environments

Bradley James Petkus

This master thesis presents a detailed overview of various MEMS accelerometers used as vibrometers in harsh environments. Commercial and scientific literature accelerometers are compared to determine the best accelerometer for said application. This compar ...

2019

CSL controls telomere maintenance and genome stability in human dermal fibroblasts

Joachim Lingner, Thomas Frédéric Lunardi, Paris Jafari

Genomic instability is a hallmark of cancer. Whether it also occurs in Cancer Associated Fibroblasts (CAFs) remains to be carefully investigated. Loss of CSL/RBP-J kappa, the effector of canonical NOTCH signaling with intrinsic transcription repressive fun ...

Springer2019

Centriole assembly at a glance

Pierre Gönczy, Georgios Hatzopoulos

The centriole organelle consists of microtubules (MTs) that exhibit a striking 9-fold radial symmetry. Centrioles play fundamental roles across eukaryotes, notably in cell signaling, motility and division. In this Cell Science at a Glance article and accom ...

2019

Redox Signaling by Reactive Electrophiles and Oxidants

Yimon Aye, Jesse Poganik

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely complex topic that has been approached from numerous different and mul ...

2018

Closed-loop Controlled Brillouin Optical Time-domain Analysis

Luc Thévenaz, Zhisheng Yang

A novel concept to retrieve information in Brillouin distributed fiber sensors is presented, in which the interacting signals are conditioned to track a uniform gain along the fiber, showing 100× faster acquisition at similar accuracy. ...

Optical Society of America2018

A model for cellular mechanotransduction and contractility at finite strain

William Curtin, Mahmut Selman Sakar, Nikolaos Bouklas

In this work we introduce a theoretical and computational modeling framework for the contractile response of single cells triggered by external mechanical stimuli. The structural response due to the formation and dissociation of stress fibers is modeled fo ...

2018

A model for cellular mechanotransduction and contractility at finite strain

William Curtin, Mahmut Selman Sakar, Nikolaos Bouklas

2018

Pulse-Stream Models In Time-Of-Flight Imaging

Jean-Philippe Thiran, Yves Wiaux, Dimitris Perdios, Adrien Georges Jean Besson

This paper considers the problem of reconstructing raw signals from random projections in the context of time-of-flight imaging with an array of sensors. It presents a new signal model, coined as multi-channel pulse-stream model, which exploits pulse-strea ...

IEEE2018

Optofluidic nanoplasmonic biosensor for label-free live cell analysis in real time

Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Maria Soler Aznar

Cell signaling activities play a critical role in physiological and disease processes. The analysis of the tumor microenvironment or the immune system activation is nowadays providing valuable insights towards disease understanding and novel therapies deve ...

2018

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