Concept

Southern blot

Publications associées (92)

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes

One of the central questions in eukaryotic transcription is how activators can transmit their signal to stimulate gene expression in the context of chromatin. The multisubunit SAGA coactivator complex has both histone acetyltransferase and deubiquitination ...

2008

A gel probe equilibrium sampler for measuring arsenic porewater profiles and sorption gradients in sediments: I. Laboratory development

Janet Gordon Hering

A gel probe equilibrium sampler has been developed to study arsenic (As) geochemistry and sorption behavior in sediment porewater. The gels consist of a hydrated polyacrylamide polymer, which has a 92% water content. Two types of gels were used in this stu ...

2008

Reduction of brain metastases in plasminogen activator inhibitor-1 deficient mice with transgenic ocular tumors

Friedrich Beermann

Plasminogen activator inhibitor-1 is known to play a paradoxical positive role in tumor angiogenesis, but its contribution to metastatic spread remains unclear. We studied the impact of PAI-1 deficiency in a transgenic mouse model of ocular tumors originat ...

Oxford University Press2008

A fully electronic label-free DNA sensor chip

Sandro Carrara, Carlotta Guiducci

This paper presents a microfabricated DNA chip for fully electronic, label-free DNA recognition, based on capacitance measurements. The chip has been fabricated in 0.5-mu m CMOS technology and it features an array of individually addressable sensing sites ...

2007

Interface Layering Phenomena in Capacitance Detection of DNA with Biochips

Giovanni De Micheli, Sandro Carrara, Carlotta Guiducci, Yusuf Leblebici, Luca Benini, Bruno Samori

Reliable DNA detection is of great importance for the development of the Lab-on-chip technology. The effort of the most recent projects on this field is to integrate all necessary operations, such as sample preparation (mixing, PCR amplification) together ...

2007

Hydrogenated amorphous silicon ultraviolet sensor for deoxyribonucleic acid analysis

Giovanni De Cesare, Carlotta Guiducci

In this letter, we show the results achieved using a hydrogenated amorphous silicon photosensor for a "label-free" deoxyribonucleic acid (DNA) analysis based on the measurements of the absorbance in the ultraviolet range. The optimization of the sensor str ...

2006

Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes

László Forró, Aleksandra Radenovic, Andras Kis

The pathological hallmarks of Alzheimer's disease (AD) consist of P-amyloid plaques and neurofibrillary tangles in affected brain areas. The processes, which drive this host reaction are unknown. To determine whether an analogous host reaction to that occu ...

Elsevier2006

Semiconductor oxide based electrodes for the label-free electrical detection of DNA hybridization: Comparison between Sb doped SnO2 and CdIn2O4

Carlotta Guiducci

First results are reported regarding the design, fabrication and operation of a DNA biochip based on a semiconductor oxide electrode that employs label-free electrical detection of the DNA hybridization. The same process of DNA functionalisation, including ...

2006

BTA, a novel reagent for DNA attachment on glass and efficient generation of solid-phase amplified DNA colonies

Gerardo Turcatti

The tricarboxylate reagent benzene-1,3,5-triacetic acid (BTA) was used to attach 5'-aminated DNA primers and templates on an aminosilanized glass surface for subsequent generation of DNA colonies by in situ solid-phase amplification. We have characterized ...

Oxford University Press2006

Isolation and characterization of Tn-Dha1, a transposon containing the tetrachloroethene reductive dehalogenase of Desulfitobacterium hafniense strain TCE1

Christof Holliger, Julien Maillard

A new 9.9 kb catabolic transposon, Tn-Dha1, containing the gene responsible for tetrachloroethene (PCE) reductive dechlorination activity, was isolated from Desulfitobacterium hafniense strain TCE1. Two fully identical copies of the insertion sequence ISDh ...

2005

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