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Bacterial pore-forming toxins: the (w)hole story?

Françoise Gisou van der Goot Grunberg, Rodrigo Manuel Gonzalez

Pore-forming toxins (PFTs) are the most common class of bacterial protein toxins and constitute important bacterial virulence factors. The mode of action of PFT is starting to be better understood. In contrast, little is known about the cellular response t ...

Birkhäuser-Verlag, Springer2008

Stress amplifies memory for social hierarchy

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

Individuals differ in their social status and societies in the extent of social status differences among their members. There is great interest in understanding the key factors that contribute to the establishment of social dominance structures. Given that ...

Frontiers Research Foundation2007

Numerical Simulation of a Class of PDAEs with a Separation of Time Scales

Benoît Chachuat

Problems that exhibit multiple time scales arise naturally in many scientific and engineering fields. For transient, distributed process systems, the corresponding models consist of partial differential equations (PDEs), possibly coupled to ordinary differ ...

Springer2007

Pore-forming toxins and cellular non-immune defenses (CNIDs)

Françoise Gisou van der Goot Grunberg

Pore-forming toxins (PFTs) are the most common class of bacterial protein toxin and are important for bacterial pathogenesis. Recent studies have shown that the previous model stating that epithelial cells lyse in response to these toxins and have no defen ...

Elsevier2007

The Dof-Box Project: An Educational Kit for Configurable Robots

Auke Ijspeert, Aude Billard, André Guignard, Olivier Barbey, Davis Daidié

This paper describes the Dof-Box, a modular, reconfigurable robot, used in Hands-on practicals of robotics taught to miroengineering students. We present the hardware and software of the robots and describe the pedagogical approach adopted in the practical ...

2007

Raptor Codes

Mohammad Amin Shokrollahi

LT-codes are a new class of codes introduced by Luby for the purpose of scalable and fault-tolerant distribution of data over computer networks. In this paper, we introduce Raptor codes, an extension of LT-codes with linear time encoding and decoding. We w ...

2006

Synthesis of uniform, non-natural oligomers

Harm-Anton Klok, Nadja Franz

Oligomers with well-defined chain lengths are of interest as foldamers, are important as model compounds for high-molecular-weight polymers and find application in electrooptic and sensory devices. This account presents an overview of the strategies that a ...

2006

A spreadsheet framework for visual exploration of biomedical datasets

Daniel Thalmann, Ronan Boulic, Sofiane Sarni, Anderson Maciel

In this paper, we present our spreadsheet framework, which uses a spreadsheet-like interface for exploring biomedical datasets. The principles and advantages of this class of visualization systems are illustrated, and a case study for the analysis of hip j ...

2005

Antigen discovery: a postgenomic approach to leprosy diagnosis

Stewart Cole

Leprosy is an infectious, neurodegenerative disease of humans caused by Mycobacterium leprae. Despite effective control programs, the incidence of leprosy remains stubbornly high, suggesting that transmission may be more common than expected. The rationale ...

2005

Raptor codes

Mohammad Amin Shokrollahi

This paper exhibits a class of universal Raptor codes: for a given integer k, and any real /spl epsiv/>0, Raptor codes in this class produce a potentially infinite stream of symbols such that any subset of symbols of size k(1 + /spl epsiv/) is sufficient t ...

2004