Concept

Clinical study design

Publications associées (32)

No difference in 13-year survival after medial pivot or central pivot mobile bearing total knee arthroplasty. A propensity matched comparative analysis

Purpose The present study was designed to evaluate the long-term results (more than 10 years) of mobile bearing total knee arthroplasty (TKA) and to compare the survival of medial pivot axis (MPA) and central pivot axis (CPA) TKAs. The primary hypothesis w ...

2020

Progress and pitfalls of using isobaric mass tags for proteome profiling

Loïc Dayon

Introduction: Quantitative proteomics using mass spectrometry is performed via label-free or label-based approaches. Labeling strategies rely on the incorporation of stable heavy isotopes by metabolic, enzymatic, or chemical routes. Isobaric labeling uses ...

TAYLOR & FRANCIS LTD2020

A causal framework for classical statistical estimands in failure-time settings with competing events

Mats Julius Stensrud

In failure-time settings, a competing event is any event that makes it impossible for the event of interest to occur. For example, cardiovascular disease death is a competing event for prostate cancer death because an individual cannot die of prostate canc ...

2020

A Telemonitoring and Hybrid Virtual Coaching Solution "CAir" for Patients with Chronic Obstructive Pulmonary Disease: Protocol for a Randomized Controlled Trial

Ádám Dániel Ivánkay

Background: Chronic obstructive pulmonary disease (COPD) is one of the most common disorders in the world. COPD is characterized by airflow obstruction, which is not fully reversible. Patients usually experience breathing-related symptoms with periods of a ...

2020

Using immersive virtual reality to support designing skills in vocational education

Pierre Dillenbourg, Jennifer Kaitlyn Olsen, Kevin Gonyop Kim, Catharine Regina Monika Maria Oertel Genannt Bierbach, Martin Dobricki

Immersive virtual reality (IVR) offers possibilities of creating a learner‐centric environment that can provide more presence and engagement for students leading to an enhanced learning experience compared to conventional classroom practices. However, the ...

2020

Repetitive Erythropoietin Treatment Improves Long-Term Neurocognitive Outcome by Attenuating Hyperoxia-Induced Hypomyelination in the Developing Brain

Yohan Van de Looij

Introduction:Preterm infants born before 28 weeks of gestation are at high risk of neurodevelopmental impairment in later life. Cerebral white and gray matter injury is associated with adverse outcomes. High oxygen levels, often unavoidable in neonatal int ...

FRONTIERS MEDIA SA2020

Motor improvement estimation and task adaptation for personalized robot-aided therapy: a feasibility study

Silvestro Micera, Jenifer Cléa Miehlbradt, Nawal Noëlle Kinany, Elvira Pirondini, Martina Coscia, Christian Giang, Camilla Pierella

Background In the past years, robotic systems have become increasingly popular in upper limb rehabilitation. Nevertheless, clinical studies have so far not been able to confirm superior efficacy of robotic therapy over conventional methods. The personaliza ...

2020

Dynamics of brain function in preterm-born young adolescents

Lorena Gonçalves de Alcântara e Freitas Krikler

Preterm birth is a major risk factor for neurodevelopment impairments often only appearing later in life. The brain is still at a high rate of development during adolescence, making this a promising window for intervention. It is thus crucial to understand ...

EPFL2020

Peptides stimulating synthesis of extracellular matrix used in anti-ageing cosmetics: Are they clinically tested? A systematic review of the literature

Florentino Luciano Caetano Dos Santos

Peptides stimulating synthesis of extracellular matrix are now commonly used in the production of anti-ageing cosmetics. However, much uncertainty still exists about the methodology of their clinical assessment. The aim of the study was to review the liter ...

WILEY2019

Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma

Stewart Cole, Anthony Vocat, Thierry Buclin, Jeff Pitteloud

The emergence of Mycobacterium tuberculosis strains resistant to current first-line antibiotic regimens constitutes a major global health threat. New treatments against multidrug-resistant tuberculosis (MDR-TB) are thus eagerly needed in particular in coun ...

PUBLIC LIBRARY SCIENCE2019

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