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Publications associées (29)

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Refinements of hybrid neurophysical volume conductor models and application to study epidural electrical stimulation of the cervical spinal cord

Nathan Antoine Greiner

After spinal cord injury (SCI), the communication between the brain and spinal neural circuits below the lesion is disrupted, leading to paralysis. Epidural electrical stimulation (EES) of the lumbosacral spinal cord has been shown to restore locomotion an ...

EPFL2020

The relevance of the artery of Adamkiewicz for microsurgical resection of spinal tumors- short overview and case series: Technical note

Constantin Tuleasca

Introduction. - There is of major interest to know the exact anatomical location of artery of Adamkiewicz (AKA) for many spinal microsurgical procedures, so as to avoid postoperative ischemia of the spinal cord, with further devastating clinical impact. Me ...

2020

Neuroprosthetic Technologies to Evaluate and Train Leg Motor Control in Neurologically Impaired Individuals

Camille Georgette Marie Le Goff-Mignardot

Spinal cord injury (SCI) disrupts many essential sensorimotor and autonomic functions. Consequently, individuals with SCI can face decades with permanent disabilities. Advances in clinical management have decreased morbidity, but no clinical trial has yet ...

EPFL2019

Soft multimodal neural interfaces for unravelling sensory neurological circuits

Frédéric Pierre Gérald Michoud

Diseases or injuries affecting the nervous system can dramatically disrupt the quality of life. Despite extensive efforts towards treating dysfunctional nervous systems, the pharmacological and electrical approaches generally involved lack the temporal and ...

EPFL2019

Automatic clustering of spinal reflexes evoked by epidural electrical stimulation of the cervical spinal cord in non-human primates

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Jocelyne Bloch, Marco Capogrosso, Beatrice Barra, Katie Zhi Zhuang, Sara Conti

Epidural electrical stimulation of the spinal cord elicits motor responses by recruiting large sensory afferents in the posterior roots. Divergence of excitatory inputs provided by these fibers generates a variety of shapes, latencies and amplitudes in the ...

2019

Regional T-1 mapping of the whole cervical spinal cord using an optimized MP2RAGE sequence

Tobias Kober

While T1 measurements present multiple challenges (robustness, acquisition time), the recently proposed MP2RAGE sequence (magnetization-prepared two rapid acquisition gradient echoes) has opened new perspectives to characterize tissue microstructure change ...

WILEY2019

Functional imaging of rostrocaudal spinal activity during upper limb motor tasks

Dimitri Nestor Alice Van De Ville, Silvestro Micera, Nawal Noëlle Kinany, Roberto Martuzzi, Elvira Pirondini

The spinal cord is the main interface between the brain and the periphery. It notably plays a central role in motor control, as spinal motoneurons activate skeletal muscles involved in voluntary movements. Yet, the spinal mechanisms underlying human moveme ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

The role of sensorimotor afferent feedback in mediating functional recovery after spinal cord injury

Kay Alexander Bartholdi

Spinal cord injury (SCI) leads to permanent deficits in sensory and motor function due to the physical disruption of descending and ascending pathways. As a consequence, spinal circuits below the level of lesion remain in an intact, but inactive state. A n ...

EPFL2019

Selective Recruitment of Arm Motoneurons in Nonhuman Primates Using Epidural Electrical Stimulation of the Cervical Spinal Cord

Stéphanie Lacour, Grégoire Courtine, Giuseppe Schiavone, Jocelyne Bloch, Marco Capogrosso, Beatrice Barra, Camille Roux

Recovery of reaching and grasping ability is the priority for people with cervical spinal cord injury (SCI). Epidural electrical stimulation (EES) has shown promising results in improving motor control after SCI in various animal models and in humans. Nota ...

2018

Advantages of soft subdural implants for the delivery of electrochemical neuromodulation therapies to the spinal cord

Stéphanie Lacour, Marco Capogrosso, Grégoire Courtine, Eduardo Martin Moraud, Pavel Musienko, Ivan Rusev Minev, Nikolaus Wenger, Jérôme Gandar, Polina Shkorbatova, Nathan Antoine Greiner

Objective. We recently developed soft neural interfaces enabling the delivery of electrical and chemical stimulation to the spinal cord. These stimulations restored locomotion in animal models of paralysis. Soft interfaces can be placed either below or abo ...

2018

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