Concept

Angela Vincent

Résumé
Angela Vincent (born 1942) is Emeritus professor at the University of Oxford and a Fellow of Somerville College, Oxford. Angela Vincent was born in 1942, the third child of Carmen and Joseph Molony (later KCVO). After St Mary's Convent, Ascot, she studied medicine at King's College London and Westminster Hospital School of Medicine (now merged with Imperial College School of Medicine). After one year as a junior doctor at St Steven's and St Charles' hospitals in London (1966–1967), she obtained an MSc in biochemistry from University College London. In 1967 she married Philip Morse Vincent and they have four children. After the MSc, she spent three frustrating years trying to fractionate rat brain synaptosomes, until she was taken on by Ricardo Miledi FRS in the biophysics department to work on acetylcholine receptors. During her five years with Miledi, her medical background helped to establish a collaboration on myasthenia gravis with John Newsom-Davis (later FRS); together at the Royal Free Hospital, London, they created a neuroimmunology group that subsequently moved with Newsom-Davis to Oxford when he was appointed action research professor of neurology. After his retirement in 1998, Vincent led the group until 2016. During this time she was head of the department of clinical neurology (2005–2008) at the University of Oxford, president of the International Society of Neuroimmunology (2001–2004), and an associate editor of Brain (2004–2013). Her research group was initially located in the Weatherall Institute of Molecular Medicine at the John Radcliffe Hospital, working on a wide range of biological disciplines encompassing molecular biology, biochemistry, cellular immunology and intracellular neurophysiology. The group's research focused on autoimmune and genetic disorders of the neuromuscular junction, peripheral nerves and more recently the exciting field of central nervous system diseases. The principal autoimmune diseases studied were myasthenia gravis, the Lambert–Eaton myasthenic syndrome, limbic encephalitis, other types of autoimmune encephalitis and acquired neuromyotonia.
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