Concept

Théories du développement

Publications associées (171)

Alkynylation with Hypervalent Iodine Reagents

Alkynes are among the most versatile functional groups in organic synthesis. They are also frequently used in chemical biology and materials science. Whereas alkynes are traditionally added as nucleophiles into organic molecules, hypervalent iodine reagent ...

Springer Verlag2015

Negative-pressure-induced enhancement in a freestanding ferroelectric

Nava Setter, Alexander Tagantsev, Marco Cantoni, Tomas Sluka, Alexander Kvasov, Silviu Cosmin Sandu, Jin Wang, Xiankui Wei, Brahim Dkhil

Ferroelectrics are widespread in technology(1), being used in electronics and communications(2), medical diagnostics and industrial automation. However, extension of their operational temperature range and useful properties is desired(3-5). Recent developm ...

Nature Publishing Group2015

Aqueous-phase hydrogenation of alkenes and arenes: The growing role of nano scale catalysts

Paul Joseph Dyson, Zhaofu Fei, Ning Yan, Sviatlana Siankevich, Safak Bulut

In this article we highlight some of the recent developments in the aqueous-phase hydrogenation of alkenes and arenes. The traditional types of water-soluble catalysts applied in aqueous media are outlined together with recent trends towards the developmen ...

Elsevier Science Bv2015

A neural approach to drugs monitoring for personalized medicine

Giovanni De Micheli, Sandro Carrara, Camilla Baj-Rossi, Marius Schirmer

The development of fast and mobile drug detection is an important aspect of personalized medicine. It enables the quick assessment of inter-individual differences in drug metabolism and corresponding adjustments of the dose. Recent developments of amperome ...

2015

Importance sampling for activity path choice

Michel Bierlaire, Antonin Danalet

We propose a model for the choice of an activity pattern. Models of activity participation patterns allow to assess the impact of demand management strategies on activity and destination choices. In particular, we focus on choice set generation of activity ...

2015

Importance sampling for activity path choice

Michel Bierlaire, Antonin Danalet

2015

Sobolev spaces in metric measure spaces: reflexivity and lower semicontinuity of slope

Maria Colombo

In this paper we make a survey of some recent developments of the theory of Sobolev spaces W-1,W-q (X, d, m), 1 < q < infinity, in metric measure spaces (X, d, m). In the final part of the paper we provide a new proof of the reflexivity of the Sobolev spac ...

2015

Engineering antigen-specific immunological tolerance

Stephane Kontos, Jeffrey Alan Hubbell, Alizée Jéléna Grimm

Unwanted immunity develops in response to many protein drugs, in autoimmunity, in allergy, and in transplantation. Approaches to induce immunological tolerance aim to either prevent these responses or reverse them after they have already taken place. We pr ...

Current Biology Ltd2015

Demonstration of a 5x5 cm(2) self-tracking solar concentrator

Eric Tremblay, Volker Günter Zagolla

Solar concentration is using optics in order to minimize the amount of expensive photovoltaic cell material needed. For concentration factors higher than approximately 4, tracking the sun's position is needed to keep the focal spot on the solar cell. Based ...

Spie-Int Soc Optical Engineering2015

Next-generation antimicrobials: from chemical biology to first-in-class drugs

Paul Murima

The global emergence of multi-drug resistant bacteria invokes an urgent and imperative necessity for the identification of novel antimicrobials. The general lack of success in progressing novel chemical entities from target-based drug screens have prompted ...

Pharmaceutical Soc Korea2015

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