Publications associées à Quinolone

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Melanie Blokesch, Loriane Bader, Mary-Claude Croisier-Coeytaux, Nicolas Olmo Flaugnatti

The type VI secretion system (T6SS) is a sophisticated, contact-dependent nanomachine involved in interbacterial competition. To function effectively, the T6SS must penetrate the membranes of both attacker and target bacteria. Structures associated with th ...

2024

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Camille Véronique Bernadette Goemans, Florian Huber

By acquiring or evolving resistance to one antibiotic, bacteria can become resistant to a second one, due to shared underlying mechanisms. This is called cross-resistance (XR) and further limits therapeutic choices. The opposite scenario, in which initial ...

2024

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Sandor Kasas, Anthony Vocat, Gino Cathomen, Eric Delarze, Florian Tagini, Laura Munch

Antimicrobial resistance (AMR) is a major public health threat, reducing treatment options for infected patients. AMR is promoted by a lack of access to rapid antibiotic susceptibility tests (ASTs). Accelerated ASTs can identify effective antibiotics for t ...

Nature Portfolio2024

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Camille Véronique Bernadette Goemans, Christian Eugen Zimmerli, Martin Beck

Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...

2024

Estrogenic, Genotoxic, and Antibacterial Effects of Chemicals from Cryogenically Milled Tire Tread

Kristin Schirmer, Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Thibault Béranger Masset

Tire and road wear particles (TRWP) contain complex mixtures of chemicals and release them to the environment,and potential toxic effects of these chemicals still need to be characterized. We used a standardized surrogate for TRWP,cryogenically milled tire ...

2024

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Alexandre Louis André Persat, Sofya Mikhaleva

Biofilm formation is generally recognized as a bacterial defense mechanism against environmental threats, including antibiotics, bacteriophages, and leukocytes of the human immune system. Here, we show that for the human pathogen Vibrio cholerae, biofilm f ...

CELL PRESS2023

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Sandor Kasas, María Inés Villalba, Allan Bonvallat, Eugenia Rossetti

Antibiotic resistance is nowadays a major public health issue. Rapid antimicrobial susceptibility tests (AST) are one of the options to fight this deadly threat. Performing AST with single-cell sensitivity that is rapid, cheap, and widely accessible, is ch ...

NATL ACAD SCIENCES2023

Material Substrate Physical Properties Control Pseudomonas aeruginosa Biofilm Architecture

Alexandre Louis André Persat, Alice Cont

The biofilm lifestyle is the most widespread survival strategy in the bacterial world. Pseudomonas aeruginosa biofilms cause chronic infections and are highly recalcitrant to antimicrobials. The genetic requirements allowing P. aeruginosa to grow into biof ...

AMER SOC MICROBIOLOGY2023

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Quinolone

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Estrogenic, Genotoxic, and Antibacterial Effects of Chemicals from Cryogenically Milled Tire Tread

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Material Substrate Physical Properties Control Pseudomonas aeruginosa Biofilm Architecture

Natural competence of the pathogen Acinetobacter baumannii: an elusive phenomenon

Identification of genes required for host-cell adhesion and antibiotic persistence of uropathogenic Escherichia coli via high-content screening

Graph Chatbot

Chattez avec Graph Search

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

Estrogenic, Genotoxic, and Antibacterial Effects of Chemicals from Cryogenically Milled Tire Tread

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

Capsular Polysaccharide Restrains Type VI Secretion in Acinetobacter baumannii

Simple optical nanomotion method for single-bacterium viability and antibiotic response testing

Material Substrate Physical Properties Control Pseudomonas aeruginosa Biofilm Architecture

Identification of genes required for host-cell adhesion and antibiotic persistence of uropathogenic Escherichia coli via high-content screening

Biofilm formation on human immune cells is a multicellular predation strategy of Vibrio cholerae

Accurate and rapid antibiotic susceptibility testing using a machine learning-assisted nanomotion technology platform

Natural competence of the pathogen Acinetobacter baumannii: an elusive phenomenon