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BSEP (ABCB11) is an ATP-binding cassette transporter that is expressed in hepatocytes and extrudes bile salts into the canaliculi of the liver. BSEP dysfunction, caused by mutations or induced by drugs, is frequently associated with severe cholestatic live ...
This paper presents the historical development of the vertical extensions of unreinforced masonry buildings in the Eixample district of Barcelona and their impact on the seismic behaviour. Existing masonry buildings of Eixample present significant seismic ...
Examining the performance of an existing bridge requires information on several aspects, such as design choices, material properties, and ongoing degradation processes. It often happens that some critical information is not available. The traditional appro ...
ABCG2 is an ATP-binding cassette (ABC) transporter whose function affects the pharmacokinetics of drugs and contributes to multidrug resistance of cancer cells. While its interaction with the endogenous substrate estrone-3-sulfate (E1S) has been elucidated ...
Principle 6 stresses that an appropriate proportion, number, organization and equitable distribution of Communal Open Spaces are essential for the sustainability of any settlement on the long-term, and should consider cultural, social and environmental asp ...
Founders benefit from identifying with their founding teams because identification facilitates cooperation in the team, aligns founders' actions with the norms and interests of the team, and, ultimately, enhances team performance. High identification with ...
Existing bridges in reinforced concrete (RC) need to be enhanced in order to comply with utilization and safety requirements of future use, in particular for higher traffic loads. Such enhancements comprise strengthening to increase the structural resistan ...
The management of existing civil infrastructure is becoming more crucial as a large share of bridges is approaching their theoretical end of service duration. Structural performance monitoring aims to verify bridge safety at a given time, and it should be ...
With the development of new materials and advanced structural analysis, alongside increasing aesthetic requirements, recent years have witnessed a trend toward longer, taller, and lighter footbridges. Different from vehicular bridges, footbridges carry rel ...
In the present paper, calcium deficient hydroxyapatite (Ca-def OHAP) has been examined in a transmission electron microscope. During the observation, the initial Ca-def OHAP was seen to transform first into a transient intermediate phase, then to a final, ...