Concept

HeLa

Publications associées (105)

Synthesis and cell localization of self-assembled dinuclear lanthanide bioprobes

Anne-Sophie Chauvin, Caroline Vandevyver, Bo Song

Lanthanide bioprobes and bioconjugates are ideal luminescent stains in view of their low propensity to photobleaching, sharp emission lines and long excited state lifetimes permitting time-resolved detection for enhanced sensitivity. In this paper, we expa ...

Royal Society, The2013

Organometallic anticancer agents that interfere with cellular energy processes: a subtle approach to inducing cancer cell death

Paul Joseph Dyson, Rosario Scopelliti, Alexey Nazarov, Mathurin Baquié, Daniel Gardini

Two hybrid compounds comprising an antimetastatic rutheniumarene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including hi ...

Royal Society of Chemistry2013

The use of fish-derived cell lines for investigation of environmental contaminants: an update following OECD’s fish toxicity testing framework No. 171.

Kristin Schirmer

Protocols for evaluating chemical toxicity at the cellular level using fish cell lines are described in this unit. Routine methodologies for growing salmonid cell lines, and using them in aquatic toxicology studies that support the mandate of the Organizat ...

wileyonlinelibrary.com2013

Amélioration de la qualité de service et évolution de la fréquentation de CarPostal

Martin Schuler, Pierre-Emmanuel Dessemontet, Antonin Danalet, Prisca Faure, Sébastien Munafò

Cette étude se situe dans le cadre dune recherche multidisciplinaire sur les pratiques modales en couronne des agglomérations mandatée par CarPostal avec pour objectif principal de mieux comprendre les pratiques de mobilité des usagers actuels et potentiel ...

2012

Photoactive sawhorse-type diruthenium tetracarbonyl complexes

Georges Wagnières, Frédéric Schmitt

Sawhorse-type diruthenium tetracarbonyl complexes incorporating carboxyphenyl porphyrin bridges and pyridine axial ligands have been prepared, characterized and evaluated as potential photosensitizing and chemotherapeutic agents in several human cancer cel ...

Elsevier2012

Holographic coherent anti-Stokes Raman scattering bio-imaging

Demetri Psaltis

CARS holography captures both the amplitude and the phase of a complex anti-Stokes field, and can perform three-dimensional imaging by digitally focusing onto different depths inside a specimen. The application of CARS holography for bio-imaging is demonst ...

2012

Hedgehog pathway regulators influence cervical cancer cell proliferation, survival and migration

Peter Martin Beard, Ivana Samarzija

Human papillomavirus (HPV) infection is considered to be a primary hit that causes cervical cancer. However, infection with this agent, although needed, is not sufficient for a cancer to develop. Additional cellular changes are required to complement the a ...

Academic Press Inc Elsevier Science2012

Encapsulation of hydrophobic pyrenyl-cycloplatinate complexes within a water-soluble arene ruthenium metalla-cage

Olivier Pierre Zava

Two hydrophobic pyrenyl-containing cycloplatinate complexes (2-(1-pyrenyl)pyridine)Pt(acac) (Pt-1) and {2-(4-(1-pyrenyl)phenyl)pyridine}Pt(acac) (Pt-2) (acac = acetylacetonato) have been encapsulated in the hexacationic water-soluble metalla-cage [(p-cymen ...

2012

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells

Paul Joseph Dyson, Michael Groessl

An approach to characterize the interactions of RAPTA-T, a novel ruthenium-based anticancer drug candidate with intriguing antimetastatic properties, with human ovarian cancer cells in vitro is described. The distribution profile of the metallodrug within ...

Royal Society of Chemistry2012

Cytotoxic Effects of Combination of Oxidosqualene Cyclase Inhibitors with Atorvastatin in Human Cancer Cells

Holger Fischer

Ten oxidosqualene c-yclase inhibitors with high efficacy as cholesterol-lowering agents and of different chemical structure classes were evaluated as potential anticancer agents against human cancer cells from various tissue origins and nontumoral human-br ...

2012

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