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Agar-agar

Publications associées (33)

Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

Microfluidic models are proving to be powerful systems to study fundamental processes in porous media, due to their ability to replicate topologically complex environments while allowing detailed, quantitative observations at the pore scale. Yet, while por ...

Hoboken2024

Biofilm morphogenesis on soft hydrogels

Alice Cont

Bacteria often colonize their environment in the form of surface attached multicellular communities called biofilms. Biofilms grow from surface-attached cells that undergo division while self-embedding in a viscoelastic matrix. Biofilms grow at the surface ...

EPFL2023

Robust and sustainable cultivation of microalgae: recycling of nitrogen from liquid digestate and control of biological contamination

Adrian Pulgarin

The present doctoral thesis aimed to achieve a robust cultivation of microalgae by recycling nitrogen from a liquid digestate. However, the use of non-sterile nutrient source increases the risks of contamination of undesired organisms such as bacteria, vir ...

EPFL2021

PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegans

Martinus Gijs, Furkan Ayhan, Hüseyin Baris Atakan

C. elegans-based assays require age-synchronized populations prior to experimentation to achieve standardized sets of worm populations, due to which age-induced heterogeneous phenotyping effects can be avoided. There have been several approaches to synchro ...

ROYAL SOC CHEMISTRY2020

Needle-free delivery of fluids from compact laser-based jet injector

Christophe Moser, Paul Delrot, Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Due to bulky actuation mechanisms, they are limited to body areas that are easy to reach such as skin. Here, we demonstrate a thin and long liq ...

2020

Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms

Johan Auwerx, Martinus Gijs, Matteo Cornaglia, Laurent Mouchiroud, Elena Katsyuba, Hüseyin Baris Atakan, Rongrong Xiang

The nematode Caenorhabditis elegans is a suitable model organism in drug screening. Traditionally worms are grown on agar plates, posing many challenges for long-term culture and phenotyping of animals under identical conditions. Microfluidics allows for ' ...

2019

Studying the roundworm Caenorhabditis elegans using microfluidic chips

Martinus Gijs

C. elegans is an attractive model organism in biology, as it shows genetic similarity with humans, facilitates microscopic observation due to its transparency, and has a short life cycle. Moreover, many mutants expressing fluorescent proteins in particular ...

SPIE-INT SOC OPTICAL ENGINEERING2019

Optical microsystems for genetically engineered biosensors. Case study: Glucose monitoring

Bakul Jitendra Vinchhi

Diabetes is a global epidemic with millions of people dying from it every year. Progress in microelectronics and machine learning has led to a huge number of FDA approvals of devices for continuous monitoring and treatment of diabetes with one product usin ...

EPFL2019

The role of mechanical hysteresis source in mechanical and mechanobiological performances of load-bearing biomaterials

Naser Nasrollahzadeh Mamaghani

Tissue engineering is a promising approach for articular cartilage regeneration as no satisfactory treatment is actually available for cartilage, partly due to the very limited self-healing capability of this tissue. To successfully induce a cartilaginous ...

EPFL2019

Cofactor sensing proteins for metabolic assays at point-of-care

Qiuliyang Yu

Miniaturized blood analysis promises a substantial improvement for the process of healthcare. However, most current blood analysis methods were developed in the context of centralized laboratories and there is a lack of robust detection technologies suitab ...

EPFL2018

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