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Publications associées (20)

Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development

Cathrin Brisken, Marian Caikovski, Alessandra Piersigilli, Dalya Ataca, Yakir Guri

The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and physiological contexts. A number of them remain 'orphan' proteases, among them ADAMTS18, which has bee ...

Company Of Biologists Ltd2016

Detection of Alzheimer’s disease amyloid-beta plaque deposition by deep brain impedance profiling

Philippe Renaud, Patrick Fraering, Amélie Barbara Hildegarde Béduer, Sébastien Mosser, Pierre Joris

OBJECTIVE: Alzheimer disease (AD) is the most common form of neurodegenerative disease in elderly people. Toxic brain amyloid-beta (ASS) aggregates and ensuing cell death are believed to play a central role in the pathogenesis of the disease. In this study ...

Iop Publishing Ltd2015

Concevoir un quartier à Lucens. Densifier une localité périurbaine tout en conservant et valorisant les échanges entres les habitants (VD)

Valentin Volery

Le projet aborde la question de la densification en milieu rural. L'énoncé a mis en évidence l'évolution morphologique des villages ainsi que celle de sa population. La migration de cette dernière rend difficile son ancrage social et, par conséquent, la pé ...

2014

An empirical study on the characterization of machined surface integrity by chip morphology in dry end-milling of titanium alloy

Muhammad Arif

Titanium alloys manifest low thermal conductivity and high work hardenability in machining. These alloys are thus considered as difficult-to-machine at higher cutting speeds and pose serious problems in machining such as degraded machined surface and rapid ...

Professional Engineering Publishing2014

Atomic force and electron microscopic-based study of sarcolemmal surface of living cardiomyocytes unveils unexpected mitochondrial shift in heart failure

Sandor Kasas

Loss of T-tubules (TT), sarcolemmal invaginations of cardiomyocytes (CMs), was recently identified as a general heart failure (HF) hallmark. However, whether IT per se or the overall sarcolemma is altered during HF process is still unknown. In this study, ...

Elsevier2014

Radiological assessment of the Tungsten Powder Test (HRM10) at HiRadMat

Nikolaos Charitonidis

Granular solid targets made of fluidised tungsten powder have been long proposed and are being studied as an alternative configuration towards high-power (>1MW beam power) target systems, suitable for a future Super Beam facility or Neutrino Factory. A fea ...

2012

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

László Forró, Aleksandra Radenovic, Andras Kis

Strong epidemiologic evidence suggests an association between Alzheimer disease (AD) and type 2 diabetes. To determine if amyloid beta (A

\beta

) and hyperphosphorylated tau occurs in type 2 diabetes, pancreas tissues from 21 autopsy cases (10 type 2 diabe ...

Elsevier2010

Effects of BDNF and other neuroprotectants on the neuropathology of Huntington's disease

Ozgün Gökce

Huntington's disease is an autosomal dominantly inherited neurodegenerative disorder characterized by progressive motor dysfunction, dementia, psychiatric symptoms, and weight loss, eventually leading to death. Postmortem analysis of the brains of HD patie ...

EPFL2009

Tissue collection for systematic phenotyping in the mouse

Johan Auwerx

In this unit, a procedure for post-mortem examination of mice and tissue collection is provided. This procedure is performed for post-mortem analysis of anatomical defects (necropsy) and histological analysis and/or tissue collection destined for molecular ...

Wiley2007

Histopathology in mouse metabolic investigations

Johan Auwerx

Due to the small size of the mouse, evaluating its clinical phenotype is sometimes problematic. In contrast, mouse models are readily accessible to post-mortem analyses at any time during the course of a disease and prior to its clinical onset. RNA, protei ...

Wiley2007

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Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

László Forró, Aleksandra Radenovic, Andras Kis

Strong epidemiologic evidence suggests an association between Alzheimer disease (AD) and type 2 diabetes. To determine if amyloid beta (A

\beta

) and hyperphosphorylated tau occurs in type 2 diabetes, pancreas tissues from 21 autopsy cases (10 type 2 diabe ...

Elsevier2010