Concept
Respiratory tract infection
Publications associées (129)
Expiratory Aerosol pH: The Overlooked Driver of Airborne Virus Inactivation
Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David, Walter Hugentobler
Respiratory viruses, including influenza virus and SARS-CoV-2, are transmitted by the airborne route. Air filtration and ventilation mechanically reduce the concentration of airborne viruses and are necessary tools for disease mitigation. However, they ign ...
2022How to: Diagnose inborn errors of intrinsic and innate immunity to viral, bacterial, mycobacterial, and fungal infections
Background: Inborn errors of intrinsic and innate immunity constitute the focus of a growing research field that investigates the molecular mechanisms underlying susceptibility to infections previously not considered part of the spectrum of inborn errors o ...
ELSEVIER SCI LTD2022Waterborne virus transport and the associated risks in a large lake
Tamar Kohn, Xavier Fernandez Cassi, Chaojie Li, Timothy R. Julian
Waterborne enteric viruses in lakes, especially at recreational water sites, may have a negative impact on human health. However, their fate and transport in lakes are poorly understood. In this study, we propose a coupled water quality and quantitative mi ...
2022Phase separation in viral infections
Viruses rely on the reprogramming of cellular processes to enable efficient viral replication; this often requires subcompartmentalization within the host cell. Liquid-liquid phase separation (LLPS) has emerged as a fundamental principle to organize and su ...
ELSEVIER SCI LTD2022Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium
Bart Deplancke, Bastien Mangeat, Vincent Roland Julien Gardeux, Julie Marie Russeil, Jörn Pezoldt, Elisa Cora, Daniel Alpern
Since its emergence in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread globally and become a major public health burden. Despite its close phylogenetic relationship to SARS-CoV, SARS-CoV-2 exhibits increased human-to- ...
PUBLIC LIBRARY SCIENCE2021Using soft aerosolization and sampling techniques for the conservation of virus infectivity during airborne exposure experiments
Athanasios Nenes, Tamar Kohn, Kalliopi Violaki, Ghislain Gilles Jean-Michel Motos, Aline Laetitia Schaub, Shannon Christa David
Recurrent epidemic outbreaks such as the seasonal flu and the ongoing COVID-19 are disastrous events to our societies both in terms of fatalities, social and educational structures, and financial losses. The difficulty to control their spread and minimize ...
2021Advances in the development of entry inhibitors for sialic-acid-targeting viruses
Francesco Stellacci, Matteo Gasbarri, Özgün Kocabiyik
Over the past decades, several antiviral drugs have been developed to treat a range of infections. Yet the number of treatable viral infections is still limited, and resistance to current drug regimens is an ever-growing problem. Therefore, additional stra ...
ELSEVIER SCI LTD2021The COUGHVID crowdsourcing dataset, a corpus for the study of large-scale cough analysis algorithms
David Atienza Alonso, Tomas Teijeiro Campo, Lara Orlandic
Cough audio signal classification has been successfully used to diagnose a variety of respiratory conditions, and there has been significant interest in leveraging Machine Learning (ML) to provide widespread COVID-19 screening. The COUGHVID dataset provide ...
2021Lung Ultrasonography for Risk Stratification in Patients with Coronavirus Disease 2019 (COVID-19): A Prospective Observational Cohort Study
Mary-Anne Hartley, Jean-Yves Meuwly
Background. Lung ultrasonography (LUS) is a promising pragmatic risk-stratification tool in coronavirus disease 2019 (COVID-19). This study describes and compares LUS characteristics between patients with different clinical outcomes. Methods. Prospective o ...
OXFORD UNIV PRESS INC2021Virucidal compositions and use thereof
Francesco Stellacci, Paulo Henrique Jacob Silva, Valeria Cagno, Özgün Kocabiyik
The invention relates to virucidal compositions comprising a sialic acid (SA) moiety, pharmaceutical compositions and disinfection and/or sterilization compositions comprising thereof and uses thereof in disinfection and/or sterilization methods and in tre ...
2021