Concept
Épanchement pleural
Publications associées (18)
Defining and targeting tumor-associated macrophages in malignant mesothelioma
Defining the ontogeny of tumor-associated macrophages (TAM) is important to develop therapeutic targets for mesothelioma. We identified two distinct macrophage populations in mouse peritoneal and pleural cavities, the monocyte-derived, small peritoneal/ple ...
NATL ACAD SCIENCES2023In situ quantification of osmotic pressure within living embryonic tissues
Sangwoo Kim, Antoine Claude Jean Vian
Mechanics is known to play a fundamental role in many cellular and developmental processes. Beyond active forces and material properties, osmotic pressure is believed to control essential cell and tissue characteristics. However, it remains very challengin ...
2023Point-of-care ultrasound for tuberculosis management in Sub-Saharan Africa-a balanced SWOT analysis
Point-of-care ultrasound (POCUS) is an increasingly accessible skill, allowing for the decentralization of its use to nonspecialist healthcare workers to guide routine clinical decision-making. The advent of ultrasound-on-a-chip has transformed the technol ...
ELSEVIER SCI LTD2022Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening center
Mary-Anne Hartley, Jean-Baptiste Francis Marie Juliette Cordonnier, Jean-Yves Meuwly, Luca Bosso, Tanguy Espejo, Siméon Schaad
Objectives Early identification of SARS-CoV-2 infection is important to guide quarantine and reduce transmission. This study evaluates the diagnostic performance of lung ultrasound (LUS), an affordable, consumable-free point-of-care tool, for COVID-19 scre ...
BMJ PUBLISHING GROUP2022Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma
Background Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer related to asbestos exposure. The tumor microenvironment content, particularly the presence of macrophages, was described as crucial for the development of the disease. This wo ...
2020Low-dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of pleural mesothelioma
Paul Joseph Dyson, Etienne Meylan, Julien Robert Rémi Faget, Aspasia Gkasti, Yameng Hao, Maxime Reichenbach
OBJECTIVES: Malignant pleural mesothelioma (MPM) is a deadly disease with limited treatment options. Approaches to enhance patient immunity against MPM have been tested but shown variable results. Previously, we have demonstrated interesting vascular modul ...
OXFORD UNIV PRESS INC2020Metabolic plasticity and glucose transporter redundancy dictate lung adenocarcinoma growth
Lung cancers represent the leading cause of cancer-related deaths worldwide. These pulmonary cancers count several histological subgroups, whose non-small cell lung cancers, subject of our study. We were precisely interested in the most common subtype of n ...
EPFL2020The combination of stereotactic radiosurgery with immune checkpoint inhibition or targeted therapy in melanoma patients with brain metastases: a retrospective study
Constantin Tuleasca, Krisztian Homicsko, Filipe Amândio Brandão Sanches Vong Martins, Olivier Michielin, Alexandre Wicky
Background Evidence pointing to a synergistic effect of stereotactic radiosurgery (SRS) with concurrent immunotherapy or targeted therapy in patients with melanoma brain metastases (BM) is increasing. We aimed to analyze the effect on overall survival (OS) ...
SPRINGER2020Vascular-targeted low dose photodynamic therapy stabilizes tumor vessels by modulating pericyte contractility
Paul Joseph Dyson, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Tina Riedel
Vascular-targeted low-dose photodynamic therapy (L-PDT) was shown to improve chemotherapy distribution in malignant pleural tumors such as malignant pleural mesothelioma (MPM). However, the mechanisms triggered by L-PDT on the tumor vasculature are still d ...
WILEY2019Tumor-associated factors are enriched in lymphatic exudate compared to plasma in metastatic melanoma patients
Davide Demurtas, Romain Hamelin, Melody Swartz, Lambert Charles François Potin, Patricia Corthésy Henrioud, Natacha Anne-Sophie Bordry, Maria Anna Sofia Broggi, Léa Maillat, Alexandre Harari
Liquid biopsies allow monitoring of cancer progression and detection of relapse, but reliable biomarkers in melanoma are lacking. Because secreted factors preferentially drain to lymphatic vessels before dilution in the blood, we hypothesized that lymph sh ...
ROCKEFELLER UNIV PRESS2019