Concept
Cytoarchitectonie
Publications associées (18)
Multimodal transcriptomic atlases of mouse spinal cord injury
A spinal cord injury (SCI) triggers a cascade of molecular and cellular responses involving inflammatory cell infiltration and cytokine release, apoptosis, demyelination, excitotoxicity, ischemia, and the formation of a fibrotic scar surrounded by an astro ...
EPFL2024Axonal projections from mouse whisker-related sensory cortex
Neurons primarily communicate through release of neurotransmitter from presynaptic specialisations along their axonal arborisations. In order to understand the functional role of a specific neuron, it is therefore of great interest to know the structure of ...
EPFL2023Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex
In the neocortex, functionally distinct areas process specific types of information. Area identity is established by morphogens and transcriptional master regulators, but downstream mechanisms driving area-specific neuronal specification remain unclear. He ...
eLIFE SCIENCES PUBL LTD2022Development of a peripheral neuroprosthesis to elicit fine hand movements in primates
Marion Aimée Geneviève Badi-Dubois
Neurological disorders such as spinal cord lesion and stroke disturb sensorimotor pathways and result in severe motor deficits that can dreadfully impact the quality of life of affected individuals. Strategies aiming at restoring hand function after upper- ...
EPFL2021A Cell Atlas for the Mouse Brain
Henry Markram, Daniel Keller, Marc-Oliver Gewaltig
Despite vast numbers of studies of stained cells in the mouse brain, no current brain atlas provides region-by-region neuron counts. In fact, neuron numbers are only available for about 4% of brain of regions and estimates often vary by as much as 3-fold. ...
2018Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex
Johannes Gräff, Jose Vicente Sanchez Mut
The brain's neocortex is anatomically organized into grey and white matter, which are mainly composed by neuronal and glial cells, respectively. The neocortex can be further divided in different Brodmann areas according to their cytoarchitectural organizat ...
Wiley-Blackwell2017Studying cyto and myeloarchitecture of the human cortex at ultra-high field with quantitative imaging: R1, R⁎2 and susceptibility
Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Diana Khabipova
In this manuscript, the use of quantitative imaging at ultra-high field is evaluated as a mean to study cyto and myelo-architecture of the cortex. The quantitative contrasts used are the longitudinal relaxation rate (R1), apparent transverse relaxation rat ...
Elsevier2017All-diamond functional surface micro-electrode arrays for brain-slice neural analysis
Ladislav Kavan, Michele Giugliano
Diamond-based microelectrode arrays were fabricated by using nanocrystalline diamond as an insulating layer and conductive boron-doped in order to used them for analysis of brain cortical slices. MEA surface is solely composed of diamond, exposed to the ce ...
Wiley-V C H Verlag Gmbh2017Multiphoton microscopy in brain imaging
Graham Knott, Bohumil Maco, Ludovico Silvestri
Brain imaging is becoming an important field in the frame of the neurophotonics in correlations with other medical ones in neuroscience studying functional and morphological aspects. In this presentation an overview on multi photon imaging of the brain wil ...
Spie-Int Soc Optical Engineering2015