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raptor is a specific and essential component of mammalian TOR complex 1 (mTORC1), a key regulator of cell growth and metabolism. To investigate a role of adipose mTORC1 in regulation of adipose and whole-body metabolism, we generated mice with an adipose-s ...
Periodic environments like we experience on the surface of planet earth lead living organisms to evolve molecular anticipation devices known a circadian clocks. The word circadian refers to the period of these oscillations which last about (circa) one day ...
A new implantable pressure sensor for long-term monitoring of intracranial pressure is presented. The sensor is powered by telemetry and can be interrogated wirelessly. A capacitive pressure transducer, whose capacitance is converted to a frequency-encoded ...
The toroidal Field Conductor Insert (TFCI) coil was tested at 46 kA in the 13 T background magnetic field generated by the Central Solenoid Model Coil. The single layer TFCI coil uses a Nb3Sn cable-in-conduit conductor in a Titanium jacket. The object of t ...
Rehydration in the triatomine bug Rhodnius prolixus (Stal) is dependent on the blood meal, and water balance regulation is crucial for survival of starving bugs. In an experimental arena with zones at different climatic conditions, starved R. prolixus nymp ...
We demonstrate high-performance nanowire superconducting single photon detectors (SSPDs) on bN thin films grown at a temperature compatible with monolithic integration. NbN films ranging from 150nm to 3nm in thickness were deposited by dc magnetron sputter ...
The target gene(s) required for Myc-mediated tumorigenesis are still elusive. Here we show that while endogenous c-Myc is surprisingly dispensable for skin homeostasis and TPA-induced hyperplasia, c-Myc-deficient epidermis is resistant to Ras-mediated DMBA ...
Lipids are important body constituents that are vital for cellular, tissue, and whole-body homeostasis. Lipids serve as crucial membrane components, constitute the body's main energy reservoir, and are important signaling molecules. As a consequence of the ...
Results of present and previous measurements of the23Na NMR response, dc- and ac-magnetic susceptibilities and the specific heat ofNa2V3O7at low temperatures suggest that this material is close to a quantum critical point (QCP) atm0H¼0 T. The experimental ...
New Road Construction Concepts (NR2C) is a project of FEHRL supported by the European Commission under the Sixth Framework Programme. This project aims at developing perspectives and specific innovations in different transport areas. One of the ideas conce ...