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By improving spatial and anatomical specificity, localized spectroscopy can enhance the power and accuracy of the quantitative analysis of cellular metabolism and bioenergetics. Localized and nonlocalized dynamic 31P magnetic resonance spectroscopy using a ...
This publication compiles the results of the SpaceWatch event 2008. The first edition has taken place in Lausanne on May 15th, 2008. The present book is composed of two parts. Part I presents the scientific comments on the press review highlighting the con ...
The aim was to investigate changes in the line width of high-energy phosphates solely originating from the intramyocellular compartment by temporally resolved localised 31P-MRS after aerobic calf muscle exercise. Semi-Laser [2] localised 31P-MRS of gastroc ...
Embryonic motoneurons from mutant SOD1 (mSOD1) mouse models of amyotrophic lateral sclerosis (ALS), but not wild-type motoneurons, can be triggered to die by exposure to nitric oxide (NO), leading to activation of a motoneuron-specific signaling pathway do ...
We describe a small-angle x-ray scattering-based imaging technique that reveals the distribution and orientation of nano-scale structures over extended areas. By combining two measurement and analysis schemes, complementary structural information is availa ...
Epigenetic silencing of essential components of DNA repair pathways is a common event in many tumor types, and comprise O6-methylguanine-DNA methyltransferase (MGMT), human mut L homolog 1 (hMLH1), Werner syndrome gene (WRN), breast cancer susceptibility g ...
Motor responses evoked by stimulating the spinal cord percutaneously between the T11 and T12 spinous processes were studied in eight human subjects during walking and running. Stimulation elicited responses bilaterally in the biceps femoris, vastus lateral ...
This paper presents a new device for a novel neurorehabilitation strategy for stroke patients suffering from upper limb paralysis. The concept consists in combining illusory movements, induced by tendon vibration on the hand and wrist, with a virtual reali ...
Multidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism ...
Perceptual learning is often considered one of the simplest and basic forms of learning in general. Accordingly, it is usually modeled with simple and basic neural networks which show good results in grasping the empirical data. Simple meets simple. Comple ...