Publications associées à Microbial phylogenetics

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. We aim ...

Nature Portfolio2024

The microbiome of cryospheric ecosystems

Tom Ian Battin, Hannes Markus Peter, Susheel Bhanu Busi, Grégoire Marie Octave Edouard Michoud, Leïla Ezzat, Massimo Bourquin, Tyler Joe Kohler, Stylianos Fodelianakis

The cryosphere includes those parts of Earth where water or soil is frozen, such as snow, ice, glaciers and permafrost soils. Here, the authors present a global inventory of cryospheric microbial communities and their genetic repertoires. The melting of th ...

NATURE PORTFOLIO2022

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

Didier Trono, Laurence Gouzi Abrami, Evaristo Jose Planet Letschert, Julien Léonard Duc, Laia Simo Riudalbas, Sandra Eloise Kjeldsen, Alexandre Coudray, Sagane Dind

The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor in the SYSCOL cohort, we ...

2022

Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load

Jacques Fellay, Luca Ferretti

Set-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising selection, with a typical opti ...

OXFORD UNIV PRESS2022

Extracting phylogenetic dimensions of coevolution reveals hidden functional signals

Anne-Florence Raphaëlle Bitbol

Despite the structural and functional information contained in the statistical coupling between pairs of residues in a protein, coevolution associated with function is often obscured by artifactual signals such as genetic drift, which shapes a protein's ph ...

NATURE PORTFOLIO2022

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Bart Deplancke, Bastien Mangeat, Vincent Roland Julien Gardeux, Julie Marie Russeil, Jörn Pezoldt, Elisa Cora, Daniel Alpern

Since its emergence in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread globally and become a major public health burden. Despite its close phylogenetic relationship to SARS-CoV, SARS-CoV-2 exhibits increased human-to- ...

PUBLIC LIBRARY SCIENCE2021

Detection of dicistroviruses RNA in blood of febrile Tanzanian children

Mary-Anne Hartley, Thomas Junier

Fever is the leading cause of paediatric outpatient consultations in Sub-Saharan Africa. Although most are suspected to be of viral origin, a putative causative pathogen is not identified in over a quarter of these febrile episodes. Using a de novo assembl ...

TAYLOR & FRANCIS LTD2019

The modern analogue of a Cretaceous coral with a calcitic skeleton

Anders Meibom, Jaroslaw Hubert Stolarski

It was argued that, in contrast to all known modern scleractinian corals that form aragonite skeletons, the original mineralogy of the Cretaceous "Coelosmilia" (ca. 70-65 Ma) was calcite during a period when the Mg2+/Ca2+ ratio of the seawater was presumab ...

2019

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Microbial phylogenetics

The microbial genomics of glacier-fed streams: adaptations to an extreme ecosystem

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

The microbiome of cryospheric ecosystems

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load

Extracting phylogenetic dimensions of coevolution reveals hidden functional signals

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Detection of dicistroviruses RNA in blood of febrile Tanzanian children

Phylogenetic correlations can suffice to infer protein partners from sequences

The modern analogue of a Cretaceous coral with a calcitic skeleton

Graph Chatbot

Chattez avec Graph Search

The microbial genomics of glacier-fed streams: adaptations to an extreme ecosystem

Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

Phylogenetic correlations can suffice to infer protein partners from sequences

Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load

The modern analogue of a Cretaceous coral with a calcitic skeleton

Detection of dicistroviruses RNA in blood of febrile Tanzanian children

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Extracting phylogenetic dimensions of coevolution reveals hidden functional signals

The microbiome of cryospheric ecosystems