Publications associées à Human serum albumin

Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions

Alessandro Angelini, Alessandro Zorzi, Sara Linciano

Human serum albumin (hSA) is the major carrier protein for fatty acids (FAs) in plasma. Its ability to bind multiple FA moieties with moderate to high affinity has inspired the use of FA conjugation as a safe and natural platform to generate long-lasting t ...

ELSEVIER2022

Comparative Analysis of Total Alpha-Synuclein (alpha SYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified alpha SYN Proteoforms

Hilal Lashuel, Lorène Aeschbach, Lara Petricca, Mohamed Bilal Fares, Ritwik Burai, Layane Hanna-el-Daher

Background: The development of therapeutics for Parkinson's disease (PD) requires the establishment of biomarker assays to enable stratifying patients, monitoring disease progression, and assessing target engagement. Attempts to develop diagnostic assays b ...

IOS PRESS2022

Promising anti-cancer potency of 4,5,6,7-tetrahydrobenzo[d]thiazole-based Schiff-bases

Kurt Schenk, Farzaneh Fadaei Tirani

Four new Schiff-bases have been synthesized from the 1:2 M condensation of 4,5,6,7-tetrahydrobenzothiazole-2,6-diamine with 2-hydroxybenzaldehyde (SL3), 5-Bromo-2-hydroxybenzaldehyde (SL2), 2-hydroxy-3-methoxybenzaldehyde (SL3) and 2-hydroxy-1-naphthaldehy ...

ELSEVIER2020

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Tobias Kober, Bénédicte Marie Maréchal

Background: Basal ganglia lesions are typical findings on magnetic resonance imaging (MRI) of the brain in survivors of acute methanol poisoning. However, no data are available on the association between the magnitude of damaged brain regions, serum concen ...

ELSEVIER2020

Continuous monitoring of propofol in human serum with fouling compensation by support vector classifier

Giovanni De Micheli, Sandro Carrara, Mandresy Ivan Ny Hanitra, Danilo Demarchi, Francesca Criscuolo, Simone Aiassa, Francesco Grassi, Tiberiu Totu, Gabriele Sandri

We present a new method for electrochemical sensing, which compensates the fouling effect of propofol through machine learning (ML) model. Direct and continuous monitoring of propofol is crucial in the development of automatic systems for control of drug i ...

2020

Novel osmium(II)-cymene complexes containing curcumin and bisdemethoxycurcumin ligands

Paul Joseph Dyson, Lucinda Kate Batchelor

The first examples of (arene)Os(II) curcuminoid derivatives have been prepared and characterized. The neutral complexes [(p-cym)Os(curc)Cl] (1) and [( p-cym)Os(bdcurc)Cl] ( 2), together with the cationic derivatives [( p-cym)Os(curc)(PTA)][SO3CF3] (3) and ...

ROYAL SOC CHEMISTRY2019

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Alessandro Angelini, Alessandro Zorzi, Sara Linciano

Peptides and small protein scaffolds are gaining increasing interest as therapeutics. Similarly to full-length antibodies, they can bind a target with a high binding affinity and specificity while remaining small enough to diffuse into tissues. However, de ...

ROYAL SOC CHEMISTRY2019

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Giovanni De Micheli, Giovanni Boero, Francesca Stradolini, Irene Taurino, Tugba Kilic

In this work, we present a novel electrochemical cleaning procedure for long-term electrochemical monitoring of propofol by using boron-doped diamond (BDD) and pencil graphite electrode (PGE). Propofol is an anesthetic that is widely used for long-lasting ...

2018

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Human serum albumin

Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions

Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes

Comparative Analysis of Total Alpha-Synuclein (alpha SYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified alpha SYN Proteoforms

An Overview of Serum Albumin Interactions with Biomedical Alloys

Promising anti-cancer potency of 4,5,6,7-tetrahydrobenzo[d]thiazole-based Schiff-bases

MRI-based brain volumetry and retinal optical coherence tomography as the biomarkers of outcome in acute methanol poisoning

Continuous monitoring of propofol in human serum with fouling compensation by support vector classifier

Novel osmium(II)-cymene complexes containing curcumin and bisdemethoxycurcumin ligands

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

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Chattez avec Graph Search

Engineering Modular 3D Liver Culture Microenvironments In Vitro to Parse the Interplay between Biophysical and Biochemical Microenvironment Cues on Hepatic Phenotypes

Molecular analysis and therapeutic applications of human serum albumin-fatty acid interactions

An Overview of Serum Albumin Interactions with Biomedical Alloys

Novel osmium(II)-cymene complexes containing curcumin and bisdemethoxycurcumin ligands

Cleaning strategy for carbon-based electrodes: Long-term propofol monitoring in human serum

Comparative Analysis of Total Alpha-Synuclein (alpha SYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified alpha SYN Proteoforms

Non-covalent albumin-binding ligands for extending the circulating half-life of small biotherapeutics