Concept
Génotypage
Publications associées (32)
Active lithoautotrophic and methane-oxidizing microbial community in an anoxic, sub-zero, and hypersaline High Arctic spring
Lost Hammer Spring, located in the High Arctic of Nunavut, Canada, is one of the coldest and saltiest terrestrial springs discovered to date. It perennially discharges anoxic (
2022Genome-wide variation in nucleotides and retrotransposons in alpine populations of Arabis alpina (Brassicaceae)
Advances in high‐throughput sequencing have promoted the collection of reference genomes and genome‐wide diversity. However, the assessment of genomic variation among populations has hitherto mainly been surveyed through single‐nucleotide polymorphisms (SN ...
2019Common genetic variants associated with Parkinson's disease display widespread signature of epigenetic plasticity
Giovanna Ambrosini, Philipp Bucher, Amit Sharma, Tikam Chand Dakal
Parkinson disease (PD) is characterized by a pivotal progressive loss of substantia nigra dopaminergic neurons and aggregation of alpha-synuclein protein encoded by the SNCA gene. Genome-wide association studies identified almost 100 sequence variants link ...
Springer2019Relationship Between Inactivation and Genome Damage of Human Enteroviruses Upon Treatment by UV254, Free Chlorine, and Ozone
Tamar Kohn, Virginie Bachmann, Suzanne Marie Young, Jason Robert Torrey
Quantitative PCR (qPCR) is a convenient tool for monitoring virus concentrations in water and wastewater treatment trains, though it only informs about virus presence, but not infectivity. This limitation can be overcome if the relationship between infecti ...
2019Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss
Bernard Schneider, Paola Andrea Solanes Vega, Sofia Carmen Suzanne Spataro
Since most dominant human mutations are single nucleotide substitutions(1,2), we explored gene editing strategies to disrupt dominant mutations efficiently and selectively without affecting wild-type alleles. However, single nucleotide discrimination can b ...
NATURE PUBLISHING GROUP2019