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Bones generate electricity under pressure, and this electromechanical behavior is thought to be essential for bone’s self-repair and remodeling properties. The origin of this response is attributed to the piezoelectricity of collagen, which is the main str ...
Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic and molecular heterogen- eity. A common issue associated with the molecular ab- normality is a disturbance in bone matrix synthesis and homeostasis inducing bone fragil ...
Swiss Medical Publishers Ltd / EMH Swiss Medical Publishers2016
The molecular mechanisms that govern bone and joint formation are complex, involving an integrated network of signaling pathways and gene regulators. We investigated the role of Hox genes, which are known to specify individual segments of the skeleton, in ...
The goal of this study is to analyze mechanical behavior of a new scaffold composed of PLA/bTCP in revision knee arhtroplasty (RKA). For this purpose, finite element models of RKA was developed to study the importance of the geometry of bones, the fixation ...
In this thesis, the potential use of fetal bone cells for tissue engineering was evaluated. At first, fetal bone cells were characterized in vitro regarding their proliferation rate, the induction of their osteoblastic phenotype, and their antigenicity. Th ...
Objective: To enable development of an endoscope for cellular-level optical imaging of the inner ear. Study Design: A prospective study of 50 cadaveric human temporal bones to define detailed surgical anatomy of the round window (RW) region and the range o ...
The shoulder complex is a complex articulation of the human body. It consists of several bones and joints and is moved and stabilized by 16 muscles. The muscle forces can not be measured experimentally, but can be computed using numerical methods. An exist ...
Human bone blood flow, mean blood speed and the number of moving red blood cells were assessed (in arbitrary units), as a function of time, during one cardiac cycle. The measurements were obtained non-invasively on five volunteers by laser-Doppler flowmetr ...
In this work a 3D musculoskeletal model of the knee joint, that can simulate a squat movement, has been developed. Such a model would be useful to understand the biomechanics of the knee. The model consisted of all the the bones with their articular surfac ...