Publications associées à Lipopolysaccharide

Antibacterial Au nanostructured surfaces

We present here a technological platform for engineering Au nanotopographies by templated electrodeposition for antibacterial surfaces. Three different types of nanostructures were fabricated: nanopillars, nanorings and nanonuggets. The nanopillars are the ...

Royal Soc Chemistry2016

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Michele De Palma, Mario Leonardo Squadrito

Despite its importance during viral or bacterial infections, transcriptional regulation of the interferon-beta gene (Ifnb1) in activated macrophages is only partially understood. Here we report that TRIM33 deficiency results in high, sustained expression o ...

Nature Publishing Group2015

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Eleonora Simeoni, Jeffrey Alan Hubbell, David Scott Wilson, Martina Damo

Dendritic cell (DC)-derived exosomes (Dexo) contain the machinery necessary to activate potent antigen-specific immune responses. As promising cell-free immunogens, Dexo have been tested in previous clinical trials for cancer vaccine immunotherapy, yet res ...

Nature Publishing Group2015

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

Pierre Magistretti, Igor Allaman

Emerging as an important correlate of neurological dysfunction in Multiple Sclerosis (MS), extended focal and diffuse gray matter abnormalities have been found and linked to clinical manifestations such as seizures, fatigue and cognitive dysfunction. To in ...

Elsevier2015

The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals

Jacques Fellay, Amalio Telenti, Istvan Bartha

Systemic immune activation, a major determinant of human immunodeficiency virus (HIV) disease progression, is the result of a complex interplay between viral replication, dysregulation of the immune system, and microbial translocation due to gut mucosal da ...

Oxford University Press2015

Inflammatory and metabolic responses to high-fat meals with and without dairy products in men

Martinus Gijs, Guy Vergères

Postprandial inflammation is an important factor for human health since chronic low-grade inflammation is associated with chronic diseases. Dairy products have a weak but significant anti-inflammatory effect on postprandial inflammation. The objective of t ...

Cambridge University Press2015

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

Nicola Harris, Mario Michael Zaiss, Ilaria Mosconi

Thymic stromal lymphopoietin (TSLP) is constitutively expressed in the intestine and is known to regulate inflammation in models of colitis. We show that steady-state TSLP expression requires intestinal bacteria and has an important role in limiting the ex ...

Nature Publishing Group2013

NutriChip: Nutrition Analysis meets Microfluidics

Martinus Gijs, Sandro Carrara, Paolo Silacci, Gözen Köklü, Julien Michel Ghaye, Hamideh Jafarpoorchekab, Christine Ruffert, Guy Vergères

This focus article introduces the concept of NutriChip, an integrated microfluidic platform for investigating the potential of the immuno-modulatory function of dairy food. The core component of the NutriChip is a miniaturized artificial human gastrointest ...

Royal Society of Chemistry2013

Engineering antigens for in situ erythrocyte binding induces T-cell deletion

Stephane Kontos, Jeffrey Alan Hubbell, Iraklis Kourtis, Karen Dane

Antigens derived from apoptotic cell debris can drive clonal T-cell deletion or anergy, and antigens chemically coupled ex vivo to apoptotic cell surfaces have been shown correspondingly to induce tolerance on infusion. Reasoning that a large number of ery ...

Natl Acad Sciences2013

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Lipopolysaccharide

Antibacterial Au nanostructured surfaces

Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals

Inflammatory and metabolic responses to high-fat meals with and without dairy products in men

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

NutriChip: Nutrition Analysis meets Microfluidics

Engineering antigens for in situ erythrocyte binding induces T-cell deletion

Graph Chatbot

Chattez avec Graph Search

Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties

Antibacterial Au nanostructured surfaces

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma

Inflammatory and metabolic responses to high-fat meals with and without dairy products in men

The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals

Intestinal bacteria induce TSLP to promote mutualistic T-cell responses

NutriChip: Nutrition Analysis meets Microfluidics

Engineering antigens for in situ erythrocyte binding induces T-cell deletion