Concept

Exploratory data analysis

Publications associées (280)

ERBIN is a new SARA-interacting protein: Competition between SARA and SMAD2 and SMAD3 for binding to ERBIN

SARA, an early endosomal protein, plays a key role in TGFβ signalling, as it presents SMAD2 and SMAD3 for phosphorylation by the activated TGFβ receptors. Here, we show that ERBIN is a new SARA-interacting protein that can be recruited by SARA to early end ...

Company of Biologists2011

Building a Front End for a Sensor Data Cloud

Karl Aberer, Zoltán Miklós, Ho Young Jeung, Michele Catasta, Ian Rolewicz

This document introduces the TimeCloud Front End, a web-based interface for the TimeCloud platform that manages large-scale time series in the cloud. While the Back End is built upon scalable, fault-tolerant distributed systems as Hadoop and HBase and take ...

Springer Berlin / Heidelberg2011

Mode choice with attitudinal latent class: a Swiss case-study

Michel Bierlaire, Aurélie Glerum, Bilge Atasoy

Attitudinal attributes play an important role in behavior of individuals in various contexts. In this study we focus on the travel behavior and our main objective is to come up with segments of individuals that have different mode choice preferences with t ...

2011

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion

Michele De Palma

Angiopoietin 2 (ANGPT2) is a proangiogenic cytokine whose expression is often upregulated by endothelial cells in tumors. Expression of its receptor, TIE2, defines a highly proangiogenic subpopulation of myeloid cells in circulation and tumors called TIE2- ...

2011

Identification and analysis of Swiss National Road tunnels pathologies

Federica Sandrone, Vincent Labiouse

In order to evaluate the general conditions (i.e. safety, serviceability and durability) of tunnels, a detailed analysis of the lining structure and surrounding rock mass is required. During the service life of the tunnel, regular survey activities should ...

Elsevier2011

Challenges and Opportunities in Self-Managing Scientific Databases

Anastasia Ailamaki, Miguel Sérgio De Oliveira Branco, Thomas Heinis, Ioannis Alagiannis, Farhan Tauheed

Advances in observation instruments and abundance of computational power for simulations encourage scientists to gather and produce unprecedented amounts of increasingly complex data. Organizing data automatically to enable efficient and unobstructed acces ...

2011

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

Michele De Palma, Ferdinando Pucci, Daniela Biziato

Vascular-disrupting agents (VDAs) such as combretastatin A4 phosphate (CA4P) selectively disrupt blood vessels in tumors and induce tumor necrosis. However, tumors rapidly repopulate after treatment with such compounds. Here, we show that CA4P-induced vess ...

2011

Hygroscopicity and composition of Alaskan Arctic CCN during April 2008

Athanasios Nenes

We present a comprehensive characterization of cloud condensation nuclei (CCN) sampled in the Alaskan Arctic during the 2008 Aerosol, Radiation, and Cloud Processes affecting Arctic Climate (ARCPAC) project, a component of the POLARCAT and International Po ...

2011

Simulation-based dynamic traffic assignment is not a black box

Gunnar Flötteröd

The dynamic traffic assignment (DTA) problem is to find the state of a transportation system where demand (travel behavior) and supply (network performance) are mutually consistent. The difficulty of solving this problem with mathematical rigor led to the ...

2011

A whole-brain voxel based measure of intrinsic connectivity contrast reveals local changes in tissue connectivity with anesthetic without a priori assumptions on thresholds or regions of interest

Roberto Martuzzi

The analysis of spontaneous fluctuations of functional magnetic resonance imaging (fMRI) signals has recently gained attention as a powerful tool for investigating brain circuits in a non-invasive manner. Correlation-based connectivity analysis investigate ...

2011

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