Concept

Traitement de la douleur

Publications associées (64)

Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients

Hannes Bleuler, Solaiman Shokur, Simon Gallo, Miguel Nicolelis

Brain-machine interfaces (BMIs) provide a new assistive strategy aimed at restoring mobility in severely paralyzed patients. Yet, no study in animals or in human subjects has indicated that long-term BMI training could induce any type of clinical recovery. ...

Nature Publishing Group2016

Surgical probe and implant development for nucleus pulposus replacements

Andreas Schmocker

Intervertebral disc degeneration is a major reason why we experience low back pain. Intervertebral discs are located in-between the vertebrae of the spine. They act, among other, as shock absorbers by distributing the mechanical load applied to the spine w ...

EPFL2016

Resonance Energy Transfer Relates the Gas-Phase Structure and Pharmacological Activity of Opioid Peptides

Vladimir Kopysov

Enkephalins are efficient pain-relief drugs that bind to transmembrane opioid receptors. One key structural param- eter that governs the pharmacological activity of these opioid peptides and is typically determined from condensed-phase structures is the di ...

Wiley-Blackwell2016

Size and Viewpoint of an Embodied Virtual Body Affect the Processing of Painful Stimuli

Olaf Blanke, Joan Llobera Mahy

Looking at one's own body might induce visual analgesia. However, the cognitive and physiological mechanisms underlying such visual analgesia are unknown. Because body and pain representations in the brain are multisensory, and have been reported to partia ...

Churchill Livingstone2015

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

Kai Johnsson, Rudolf Hovius, Katarzyna Irena Gorska, Giulia Miracca

Human genetic studies have revealed an association between GTP cyclohydrolase 1 polymorphisms, which decrease tetrahydrobiopterin (BH4) levels, and reduced pain in patients. We now show that excessive BH4 is produced in mice by both axotom- ized sensory ne ...

Elsevier2015

Adverse tissue reaction to corrosion at the neck-stem junction after modular primary total hip arthroplasty

Stefano Mischler, Pierre Mettraux

Complications related to the neck-stem junction of modular stems used for total hip arthroplasty (THA) are generating increasing concern. A 74-year-old male had increasing pain and a cutaneous reaction around the scar 1 year after THA with a modular neck-s ...

Elsevier Masson2015

A patient-specific numerical musculoskeletal knee model

Adeliya Latypova

Total Knee Arthroplasty (TKA) is a well-accepted surgical treatment of severe cases of osteoarthritis. Surgery is associated with improved pain level, knee function and health-related quality of life. Despite advances in surgical techniques and implant des ...

EPFL2015

Automatic Hand Phantom Map Detection Methods

Christian Enz, Claudio Bruschini, Huaiqi Huang, Tao Li, Jörn Justiz

Many amputees have maps of referred sensation from their missing hand on their residual limb (phantom maps). This skin area can serve as a target for providing amputees with tactile sensory feedback. Providing tactile feedback on the phantom map can improv ...

2015

Comparison of anterior cingulate vs. insular cortex as targets for real-time fMRI regulation during pain stimulation

Dimitri Nestor Alice Van De Ville, Kirsten Emmert

Real-time functional magnetic resonance imaging (rt-fMRI) neurofeedback allows learning voluntary control over specific brain areas by means of operant conditioning and has been shown to decrease pain perception. To further increase the effect of rt-fMRI n ...

Frontiers Research Foundation2014

Trigeminal Neuralgia Related to Megadolichobasilar Artery Compression: A Prospective Series of Twenty-Nine Patients Treated with Gamma Knife Surgery, with More Than One Year of Follow-Up

Constantin Tuleasca, Anne Donnet

Background: Trigeminal neuralgia (TN) secondary to megadolichobasilar artery (MBA) compression is considerably difficult to manage surgically. Objective: This study aims to evaluate the safety/efficacy of Gamma Knife surgery (GKS) in this special group of ...

Karger2014

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