Publications associées à Substitute good

Solid-phase peptide synthesis in 384-well plates

Christian Heinis, Anne Sofie Luise Zarda, Alexander Lund Nielsen, Sevan Mleh Habeshian, Gontran Sangouard, Mischa Schüttel, Edward Jeffrey Will

Newer solid-phase peptide synthesis and release strategies enable the production of short peptides with high purity, allowing direct screening for desired bioactivity without prior chromatographic purification. However, the maximum number of peptides that ...

2024

Azide-Containing Hypervalent Iodine Reagents for Biomolecules Functionalization

Raphaël Michel Henri Simonet-Davin

The goal of my PhD was the development of a new method for unselective surface labeling, not substrate-specific, that would give access to direct visualization of any surface interactions. In order to achieve this challenging goal, we wanted to develop a g ...

EPFL2022

Tuning stiffness nonlinearty: theory and applications

Simon Nessim Henein, Ilan Vardi, Mohamed Gamal Abdelrahman Ahmed Zanaty

Perfect elasticity is not achievable in real-life situation, so spring stiffness is not perfectly constant. In this paper, we study the effect of modifying non-linear stiffness terms while keeping the nominal stiffness constant. We introduce three methods ...

ASME2020

Fiscal Policy, Relative Prices and Net Exports in a Currency Union

Luisa Lambertini, Christian Pröbsting

This paper studies the effects of fiscal policy on net exports, the terms of trade and expenditure switching. Using data on government spending and consumption taxes for twelve euro area countries over 1996 to 2018, it shows that fiscal austerity shocks im ...

2020

Artificial Muscles: Dielectric Elastomers Responsive to Low Voltages

Yauhen Sheima

The lack of soft high-dielectric-permittivity elastomers responsive to a low voltage has been a long-standing obstacle for the industrialization of dielectric elastomer actuators (DEA) technology. Here, elastomers that not only possess a high dielectric pe ...

WILEY-V C H VERLAG GMBH2019

Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials

Jeffrey Alan Hubbell, Peter Frey, Hans Mattias Larsson, Priscilla Suhasna Maithili Briquez, Kristen Lorentz

Aprotinin is a broad-spectrum serine protease inhibitor used in the clinic as an anti-fibrinolytic agent in fibrin-based tissue sealants. However, upon re-exposure, some patients suffer from hypersensitivity immune reactions likely related to the bovine or ...

2017

A linear programming approach to the optimization of residential energy systems

Jan Van Herle, Daniel Kuhn, Dirk Lauinger, Priscilla Caliandro

A decision-support tool (ORES) in the form of a linear program is developed to determine the optimal investment and operating decisions for residential energy systems. It shows how energy conversion units such as a cogeneration fuel cell, a heat pump, a bo ...

2016

A Non-Parametric Approach to Demand Forecasting in Revenue Management

Shadi Sharif Azadeh

In revenue management, the profitability of the inventory and pricing decisions rests on the accuracy of demand forecasts. However, whenever a product is no longer available, true demand may differ from registered bookings, thus inducing a negative bias in ...

2015

In silico assessment of the HPLC-UV response coefficients

Eric Albert Georges Bremond

A new in silica approach allowing to compute HPLC-UV response coefficients using Time Dependent-Density Functional Theory (TD-DFT) is here reported. Based on the use of a non linear least squares with bound restricted algorithm, this model exploits theoret ...

Elsevier Science Bv2014

Frequency capping in online advertising

Moran Feldman

We study the following online problem. There are n advertisers. Each advertiser has a total demand and a value for each supply unit. Supply units arrive one by one in an online fashion, and must be allocated to an agent immediately. Each unit is associated ...

Springer2014