Concept

G1 phase

Publications associées (32)

Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs

Daniel Constam, Benjamin Marcel Daniel Rothé, Simon Fortier, Céline Gagnieux, Céline Emmanuelle Schmuziger

The growing number of diseases linked to aberrant phase transitioning of ribonucleoproteins highlights the need to uncover how the interplay between multivalent protein and RNA interactions is regulated. Cytoplasmic granules of the RNA binding protein Bica ...

CELL PRESS2023

Evaluation of 30 urban land surface models in the Urban-PLUMBER project: Phase 1 results

Gabriele Manoli, Matthias Roth

Accurately predicting weather and climate in cities is critical for safeguarding human health and strengthening urban resilience. Multimodel evaluations can lead to model improvements; however, there have been no major intercomparisons of urban-focussed la ...

Wiley2023

Exploring the mechanisms governing nuclear cGAS localization and activity

Marilena Wischnewski

Recognition of pathogen-derived molecules through germline-encoded receptors is a fundamental principle of innate immunity. Pattern recognition receptors detect specific intracellular danger signals to trigger potent immune responses. The DNA sensor cyclic ...

EPFL2022

Natural competence of the pathogen Acinetobacter baumannii: an elusive phenomenon

Nina Vesel

Natural competence for transformation is an important driver of horizontal DNA exchange between different organisms. This can result in accumulation of dangerous genetic features, such as antibiotic resistance genes, in a single organism. One example of an ...

EPFL2022

Step Change Detection for Improved ROCOF Evaluation of Power System Waveforms

Mario Paolone, Asja Derviskadic, Alexandra Cameron Karpilow, Guglielmo Frigo

In the analysis of power grid waveforms, the presence of amplitude or phase steps can disrupt the estimation of frequency and rate-of-change-of-frequency (ROCOF). Standard methods based on phasor-models fail in the extraction of signal parameters during th ...

IEEE2022

Disorder-induced electronic, magnetic, and optoelectronic properties of two-dimensional materials

Cheol Yeon Cheon

Technological advancement has been in cadence with material development by improving the purity of single crystals and, at the same time, controlling their imperfections. These capabilities have been especially vital for developing new technolo-gies based ...

EPFL2022

An Inverse-Filter-Based Method to Locate Partial Discharge Sources in Power Transformers

Farhad Rachidi-Haeri, Marcos Rubinstein, Hamidreza Karami

Partial discharge (PD) occurrence in power transformers can lead to irreparable damage to the power network. In this paper, the inverse filter (IF) method to localize PDs in power transformers is proposed. To the best of the authors’ knowledge, this is the ...

2022

Pilus production in Acinetobacter baumannii is growth phase dependent and essential for natural transformation

Melanie Blokesch, Nina Vesel

Acinetobacter baumannii is a severe threat to human health as a frequently multidrug-resistant hospital-acquired pathogen. Part of the danger from this bacterium comes from its genome plasticity and ability to evolve quickly by taking up and recombining ex ...

American Society for Microbiology2021

Microstructure Selection in Laser Remelted Fe-C-Si Alloys

Wilfried Kurz, Philippe Gilgien

Laser surface remelting at various velocities has been employed to study the selection of microstructures of high-purity Fe-C-Si alloys containing nominally 3.2 to 4.2 wt.% C and 1 to 3 wt.% Si. The microstructure of the remelted region consisted of metast ...

WALTER DE GRUYTER GMBH2021

Intraductal xenografts model estrogen receptor-positive (ER+) breast cancer dormancy and reveal a critical role for epithelial-mesenchymal transition (EMT) in its establishment

Patrik Aouad

Compared to estrogen receptor-negative (ER-) breast cancer (BC), ER+ BC often manifests with a latent disease that recurs decades after initial diagnosis. The mechanisms governing dormancy and distant recurrence of ER+ tumors remain elusive due to the lack ...

EPFL2021