Concept
Cytochrome b
Publications associées (24)
Implementation of a flavin biosynthesis operon improves extracellular electron transfer in bioengineered Escherichia coli
Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib
Bioelectrochemical systems (BES) are promising for energy, sensing, environmental, and synthesis applications. Escherichia coli were previously bioengineered for application in BES by introduction of extracellular electron transfer (EET) pathways. Inspired ...
2023Engineering extracellular electron transfer for enhanced energy harvesting in microbial electrochemical devices
Microorganisms known as exoelectrogens evolved the ability of transporting electrons across insulating biological membranes. In a physiological context, this enables respiration on extracellular electron acceptors and electron transfer to other organisms. ...
EPFL2023Mechanism of Reduction of Aqueous U(V)-dpaea and Solid-Phase 2 U(VI)-dpaea Complexes: The Role of Multiheme c‑Type Cytochromes
Marinella Mazzanti, Rizlan Bernier-Latmani, Karin Lederballe Meibom, Margaux Camille Andréa Molinas, Radmila Faizova
The biological reduction of soluble U(VI) complexes to form immobile U(IV) species has been proposed to remediate contaminated sites. It is well established that multiheme c-type cytochromes (MHCs) are key mediators of electron transfer to aqueous phase U( ...
2023Insights into the microbial reduction of pentavalent and hexavalent uranium species by Shewanella oneidensis MR-1
Margaux Camille Andréa Molinas
Decades of uranium-related activities such as ore mining, nuclear power generation, weapon manufacture, storage of nuclear wastes, have contributed to the release of U in the environment. U occurrence is concerning, since in surface environments, U is typi ...
EPFL2021Conditional essentiality of a complex I-like enzyme in strict anaerobes: the case of Desulfitobacterium
Christof Holliger, Julien Maillard, Romain Hamelin, Mathilde Stéphanie Willemin, Florence Armand
Respiratory complex I is a well-known player in aerobic respiration; it couples the transfer of two electrons from NADH to ubiquinone alongside with proton pumping. Bacterial complex I is usually composed of fourteen subunits forming three different module ...
2021New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis
Stewart Cole, Andrej Benjak, Anthony Vocat, Jérémie Piton, Shi-Yan Caroline Foo, Andréanne Lupien
The emergence of multi-drug (MDR-TB) and extensively-drug resistant tuberculosis (XDR-TB) is a major threat to the global management of tuberculosis (TB) worldwide. New chemical entities are of need to treat drug-resistant TB. In this study, the mode of ac ...
2020The small RNA RyhB is a regulator of cytochrome expression in Shewanella oneidensis
Rizlan Bernier-Latmani, Karin Lederballe Meibom
Shewanella oneidensis produces an extensive electron transfer network that results in metabolic flexibility. A large number of c-type cytochromes are expressed by S. oneidensis and these function as the fundamental electron transport chain proteins. Althou ...
2018Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
Stewart Cole, Andrej Benjak, Anthony Vocat, Jérémie Piton, Shi-Yan Caroline Foo, Andréanne Lupien, Raphael Christopher Sommer
New drugs are needed to control the current tuberculosis (TB) pandemic caused by infection with Mycobacterium tuberculosis. We report here on our work with AX-35, an arylvinylpiperazine amide, and four related analogs, which are potent antitubercular agent ...
AMER SOC MICROBIOLOGY2018Non-invasive continuous monitoring of pro-oxidant effects of engineered nanoparticles on aquatic microorganisms
Olivier Martin, Paul Bowen, Christian Santschi, Volodymyr Koman, Nadia Rachel Von Moos
Engineered nanomaterials (ENMs) are key drivers for the development of highly sophisticated new technologies. As all new attainments, the rapidly increasing used of ENMs raise concerns about their safety for the environment and humans. There is growing evi ...
2017Photo-induced oxidation of the uniquely liganded heme f in the cytochrome b(6)f complex of oxygenic photosynthesis
Frank van Mourik, Andre Al Haddad, Adrien Alexis Paul Chauvet, Rachna Agarwal
The ultrafast behavior of the ferrous heme f from the cytochrome b(6)f complex of oxygenic photosynthesis is revealed by means of transient absorption spectroscopy. Benefiting from the use of microfluidic technologies for handling the sample as well as fro ...
Royal Society of Chemistry2016