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Publications associées (41)
Metal reduction and sporulation in Desulfotomaculum reducens
The genera Desulfotomaculum and Clostridium, belonging to the phylum Firmicutes, comprise Gram-positive, low G+C genomic content, anaerobic, spore- forming bacteria. Desulfotomaculum is a metabolically and environmentally versatile genus capable of growing ...
EPFL2014Kinetic reconstruction and analysis of sphingolipid metabolism
Vassily Hatzimanikatis, Howard Riezman, Georgios Savoglidis
Lipids are major constituents of the cell, implicated with its functional and structural properties, along with a number of chronic diseases. Applying computational techniques with systematic modeling of lipids can provide insights about mechanisms that re ...
2014New alternatives for the fermentation process in the ethanol production from sugarcane: Extractive and low temperature fermentation
Ethanol is produced in large scale from sugarcane in Brazil by fermentation of sugars and distillation. This is currently considered as an efficient biofuel technology, leading to significant reduction on greenhouse gases emissions. However, some improveme ...
Elsevier2014Detection of Drug-Protein Interactions with an Improved Yeast Three-Hybrid System
The identification of the targets of therapeutic drugs is one of the major challenges for pharmaceutical companies. The main target responsible for drug action is often known, but most drugs also bind other targets, either causing deleterious side effects ...
EPFL2013Bioethanol production from oil palm empty fruit bunches
Face to the increasing demand for energy, the declining availability of fossil fuels and the periodical tensions in the geopolitical context of oil-producing countries have raised serious concerns in the governments worldwide as well as in the public opini ...
EPFL2012Taxonomic characterisation of Pseudomonas strain L48 and formal proposal of Pseudomonas entomophila sp nov.
An entomopathogenic, Gram-negative bacterium isolated from a female specimen of the fruit fly Drosophila melanogaster was taxonomically characterised. Strain L48(T) was strictly aerobic, non-fermentative, oxidase and catalase positive, rod-shaped, and moti ...
Elsevier2012GTPase Activity Plays a Key Role in the Pathobiology of LRRK2
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are associated with late-onset, autosomal-dominant, familial Parkinson's disease (PD) and also contribute to sporadic disease. The LRRK2 gene encodes a large protein with multiple domains, includin ...
Public Library of Science2010Fuel bioethanol production from whey permeate
The objective of this thesis was to evaluate the feasibility for the production of fuel bioethanol from whey permeate. The identification of the limiting factors of the process revealed that the stabilization of the substrate was critical to the use of whe ...
EPFL2009Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping
Yeast one-hybrid (Y1H) assays provide a gene-centered method for the identification of interactions between gene promoters and regulatory transcription factors (TFs). To date, Y1H assays have involved library screens that are relatively expensive and labor ...
2007Differentiation of Trophoblast Giant Cells and Their Metabolic Functions Are Dependent on Peroxisome Proliferator-Activated Receptor /
Mutation of the nuclear receptor peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) severely affects placenta development, leading to embryonic death at embryonic day 9.5 (E9.5) to E10.5 of most, but not all, PPARbeta/delta-null mutant ...
American Society for Microbiology2006