Concept

Conjugaison (génétique)

Publications associées (108)

Mechanistic aspects of DNA uptake in naturally competent Vibrio cholerae

The physiological state of competence for natural transformation allows bacteria to take up free DNA from the environment and recombine it into their genome. As one of three modes of horizontal gene transfer, natural transformation has hence contributed su ...

EPFL2014

Combined scanning transmission X-ray and electron microscopy for the characterization of bacterial endospores

Rizlan Bernier-Latmani, Elena Suvorova Buffat, Paul Pao-Yun Shao, Imrich Barak, Jan Jamroskovic

Endospores (also referred to as bacterial spores) are bacterial structures formed by several bacterial species of the phylum Firmicutes. Spores form as a response to environmental stress. These structures exhibit remarkable resistance to harsh environmenta ...

Wiley-Blackwell2014

Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria

Melanie Blokesch, Patrick Martin Seitz

Bacterial genomics is flourishing, as whole-genome sequencing has become affordable, readily available, and rapid. As a result, it has become clear how frequently horizontal gene transfer (HGT) occurs in bacteria. The potential implications are highly sign ...

Wiley-Blackwell2013

Metabolomics of hexachlorocyclohexane (HCH) transformation: ratio of LinA to LinB determines metabolic fate of HCH isomers

Christof Holliger

Although the production and use of technical hexachlorocyclohexane (HCH) and lindane (the purified insecticidal isomer -HCH) are prohibited in most countries, residual concentrations still constitute an immense environmental burden. Many studies describe t ...

Wiley-Blackwell2013

Interactions of core-shell quantum dots with metal resistant bacterium Cupriavidus metallidurans: Consequences for Cu and Pb removal

Miguel Garcia

In the present study we address the interactions of carboxyl-CdSe/ZnS core/shell quantum dots (QDs), as a model of water dispersible engineered nanoparticles, and metal resistant bacteria Cupriavidus metallidurans, largely used in metal decontamination. Th ...

Elsevier Science Bv2013

Microbial diversity differences within aerobic granular sludge and activated sludge flocs

In this study, we investigated during 400 days the microbial community variations as observed from 16S DNA gene DGGE banding patterns from an aerobic granular sludge pilot plant as well as the from a full-scale activated sludge treatment plant in Epe, the ...

Springer2013

Dynamic Persistence of Antibiotic-Stressed Mycobacteria

John McKinney, Neeraj Dhar, François Signorino-Gelo, Katrin Esther Schneider

Exposure of an isogenic bacterial population to a cidal antibiotic typically fails to eliminate a small fraction of refractory cells. Historically, fractional killing has been attributed to infrequently dividing or nondividing "persisters." Using microflui ...

Amer Assoc Advancement Science2013

A transcriptional regulator linking quorum sensing and chitin induction to render Vibrio cholerae naturally transformable

Melanie Blokesch, Mirella Lo Scrudato

The human pathogen Vibrio cholerae is an aquatic bacterium associated with zooplankton and their chitinous exoskeletons. On chitinous surfaces, V. cholerae initiates a developmental programme, known as natural competence, to mediate transformation, which i ...

Oxford University Press2013

A problem of persistence: still more questions than answers?

John McKinney

The current antibiotic resistance crisis has led to increased pressure to prioritize strategies to tackle the issue, with a strong focus being placed on the development of novel antimicrobials. However, one major obstacle that is often overlooked is persis ...

Nature Publishing Group2013

DNA-uptake machinery of naturally competent Vibrio cholerae

Melanie Blokesch, Patrick Martin Seitz

Natural competence for transformation is a mode of horizontal gene transfer that is commonly used by bacteria to take up DNA from their environment. As part of this developmental program, so-called competence genes, which encode the components of a DNA-upt ...

National Academy of Sciences2013

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