Publications associées à Monocyte

Cancer metastasis: Perivascular macrophages under watch

TIE2-expressing macrophages cluster around blood vessels and sustain tumor angiogenesis. Harney and colleagues now use live imaging of mouse mammary tumors to show that these perivascular macrophages also promote the transient opening of tumor blood vessel ...

American Association for Cancer Research2015

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Nicola Harris, Julia Esser-von Bieren

Over 25% of the world's population are infected with helminth parasites, the majority of which colonise the gastrointestinal tract. However, no vaccine is yet available for human use, and mechanisms of protective immunity remain unclear. In the mouse model ...

Public Library of Science2015

Vascular Modulatory Functions of Macrophages

Michele De Palma, Ioanna Keklikoglou

Monocytes/macrophages have long been regarded as important regulators of angiogenesis and vascular remodeling in both developmental and pathological processes. Historically, the ability of macrophages to promote vascular growth has been primarily attribute ...

Springer2014

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

Michele De Palma, Mario Leonardo Squadrito

The immunosuppressive tumor microenvironment represents a major hurdle to cancer therapy. We developed a gene transfer strategy into hematopoietic stem cells (HSCs) to target transgene expression to tumor-infiltrating monocytes/macrophages. Using a combina ...

2014

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

Eva Sabrina Gollwitzer, Nicola Harris, Benjamin John Marsland

Metabolites from intestinal microbiota are key determinants of host-microbe mutualism and, consequently, the health or disease of the intestinal tract. However, whether such host-microbe crosstalk influences inflammation in peripheral tissues, such as the ...

Nature Publishing Group2014

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

Jacques Fellay, Amalio Telenti

Natural progression of HIV-1 infection depends on genetic variation in the human major histocompatibility complex (MHC) class I locus, and the CD8(+) T cell response is thought to be a primary mechanism of this effect. However, polymorphism within the MHC ...

Public Library of Science2014

Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade

Michele De Palma, Céline Wyser Rmili, Ioanna Keklikoglou, Ece Kadioglu, Nicolo Rigamonti

Angiopoietin-2 (ANG2/ANGPT2) is a context-dependent TIE2 receptor agonist/antagonist and proangiogenic factor. Although ANG2 neutralization improves tumor angiogenesis and growth inhibition by vascular endothelial growth factor (VEGF)-A signaling blockade, ...

Elsevier2014

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb

Michele De Palma, Daniela Biziato

A third of patients with critical limb ischemia (CLI) will eventually require limb amputation. Therapeutic neovascularization using unselected mononuclear cells to salvage ischemic limbs has produced modest results. The TIE2-expressing monocytes/macrophage ...

Wiley-Blackwell2013

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Monocyte

Cancer metastasis: Perivascular macrophages under watch

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Vascular Modulatory Functions of Macrophages

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection

Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade

Crystal Structure and Solution Species of Ce(III) and Ce(IV) Formates: From Mononuclear to Hexanuclear Complexes

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb

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Chattez avec Graph Search

Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection

Cancer metastasis: Perivascular macrophages under watch

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

HTT-lowering reverses Huntington's disease immune dysfunction caused by NF kappa B pathway dysregulation

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb

Crystal Structure and Solution Species of Ce(III) and Ce(IV) Formates: From Mononuclear to Hexanuclear Complexes

Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade

Vascular Modulatory Functions of Macrophages

LILRB2 Interaction with HLA Class I Correlates with Control of HIV-1 Infection