Publications associées à Monocyte

Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study

Jacques Fellay, Christian Axel Wandall Thorball

Leukocyte count is associated with coronary artery disease (CAD) events in the general population. Here we show that leukocytes are independently associated with CAD events in people with HIV in Switzerland, after adjusting for traditional and HIVrelated r ...

OXFORD UNIV PRESS INC2023

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Florian Maria Wurm, Guillaume Raussin

Intracellular lipid droplets (LDs) can accumulate in response to inflammation, metabolic stresses, and other physiological/pathological processes. Herein, we investigated whether spike proteins of SARS-CoV-2 induce LDs in human peripheral blood mononuclear ...

Basel2023

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

Florence Pojer, George Coukos, Kelvin Ka Ching Lau, Amédé Noredine Larabi, Julien Racle, David Gfeller, Marta Andreia Da Silva Perez, Alexandre Harari

CD4+T cells orchestrate the adaptive immune response against pathogens and cancer by recognizing epitopes presented on class II major histocompatibility complex (MHC-II) molecules. The high polymorphism of MHC-II genes represents an important hurdle toward ...

CELL PRESS2023

Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

Grégoire Courtine, Jordan Squair, Claudia Kathe, Yi Ding

After spinal cord injury, tissue distal to the lesion contains undamaged cells that could support or augment recovery. Targeting these cells requires a clearer understanding of their injury responses and capacity for repair. Here, we use single nucleus RNA ...

NATURE PORTFOLIO2022

A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila

Bruno Lemaitre, Samuel Rommelaere, Florent François Masson, Bianca Marie Petrignani

Programmed cell death plays a fundamental role in development and tissue homeostasis. Professional and non-professional phagocytes achieve the proper recognition, uptake, and degradation of apoptotic cells, a process called efferocytosis. Failure in effero ...

2021

In Situ Biostimulation of Cr(VI) Reduction in a Fast-Flowing Oxic Aquifer

Rizlan Bernier-Latmani, Daniel Scott Alessi

Hexavalent chromium is among the most common and hazardous inorganic contaminants in soils and groundwater. A promising in situ bioremediation approach is the delivery of electron donors to stimulate microbially mediated Cr(VI) reduction, producing relativ ...

AMER CHEMICAL SOC2020

Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis

Johan Auwerx, Antoine Jalil

Mitochondria have emerged as key actors of innate and adaptive immunity. Mitophagy has a pivotal role in cell homeostasis, but its contribution to macrophage functions and host defense remains to be delineated. Here, we showed that lipopolysaccharide (LPS) ...

AMER SOC CLINICAL INVESTIGATION INC2020

Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1

Johan Auwerx, Matthias Alexander Sokrates Stein, Julien Weber, Tasneem Arsiwala

Aims: Sirtuin 6 (Sirt6) is a NAD(+)-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors is ...

2020

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Monocyte

Defining and targeting tumor-associated macrophages in malignant mesothelioma

Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

New approaches to uncover the minimally functional hematopoietic niche using the adipocytic differentiation axis: pharmacological modulation and adrenal niche induction

A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila

In Situ Biostimulation of Cr(VI) Reduction in a Fast-Flowing Oxic Aquifer

Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis

Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1

Graph Chatbot

Chattez avec Graph Search

Human PBMCs Form Lipid Droplets in Response to Spike Proteins

New approaches to uncover the minimally functional hematopoietic niche using the adipocytic differentiation axis: pharmacological modulation and adrenal niche induction

Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

In Situ Biostimulation of Cr(VI) Reduction in a Fast-Flowing Oxic Aquifer

Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

Inhibition of mitophagy drives macrophage activation and antibacterial defense during sepsis

A secreted factor NimrodB4 promotes the elimination of apoptotic corpses by phagocytes in Drosophila

Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1