Publications associées à Stratégie nucléaire

Comprehensive analysis of the circadian nuclear and cytoplasmic transcriptome in mouse liver

Felix Naef, Cédric Gobet, Benjamin Dieter Weger, Clémence Yumie Syloun Hurni

In eukaryotes, RNA is synthesised in the nucleus, spliced, and exported to the cytoplasm where it is translated and finally degraded. Any of these steps could be subject to temporal regulation during the circadian cycle, resulting in daily fluctuations of ...

PUBLIC LIBRARY SCIENCE2022

Chemical Cell Surface Modification and Analysis of Nanoparticle-Modified Living Cells

Harm-Anton Klok, Tanja Thomsen

Cells are promising as carriers that can enhance the delivery of nanomedicines. Cells that carry nanomedicinal cargo, either immobilized on the cell surface or internalized, can allow for highly specific delivery and can enable the transport of nanomedicin ...

AMER CHEMICAL SOC2021

A synchrotron X-ray imaging strategy to map large animal brains

Giorgio Margaritondo, Ying Chen

Mapping the large neural networks of animal and human brains is a fundamental but so far elusive task, because of the massive amount of data and the consequent prohibitively long image taking and processing times. We developed an effective strategy called ...

2020

Synthesis, reactivity, and environmental relevance of uranyl(V) complexes

Radmila Faizova

Knowledge of fundamental chemical properties of all environmentally relevant uranium species is essential to understand environmental uranium mobility and develop novel remediation strate-gies. A myriad of uranium(VI) and uranium(IV) compounds has been stu ...

EPFL2020

Resource Management for Power-Constrained HEVC Transcoding Using Reinforcement Learning

David Atienza Alonso, Marina Zapater Sancho, Arman Iranfar, Luis Maria Costero Valero

The advent of online video streaming services along with the users' demand for high-quality contents require High Efficiency Video Coding (HEVC), which provides higher quality and compression at the cost of increased complexity. On one hand, HEVC exposes a ...

2020

Probing strongly hybridized nuclear-electronic states in a model quantum ferromagnet

Henrik Moodysson Rønnow, Giovanni Boero, Peter Babkevich, Julian Piatek, Ivan Kovacevic

We present direct local-probe evidence for strongly hybridized nuclear-electronic spin states of an Ising ferromagnet LiHoF4 in a transverse magnetic field. The nuclear-electronic states are addressed via a magnetic resonance in the GHz frequency range usi ...

2016

A SIRT7-Dependent Acetylation Switch of GABPβ1 Controls Mitochondrial Function

Johan Auwerx, Kristina Schoonjans, Alessia Perino, Dongryeol Ryu, Hongbo Zhang, Matthias Alexander Sokrates Stein, Giuseppe Lo Sasso

Mitochondrial activity is controlled by proteins encoded by both nuclear and mitochondrial DNA. Here, we identify Sirt7 as a crucial regulator of mitochondrial homeostasis. Sirt7 deficiency in mice induces multisystemic mitochondrial dysfunction, which is ...

Cell Press2014

Energy-Efficient Opportunistic Collaborative Sensing

Karl Aberer, Zhixian Yan, Julien Eberle

This paper studies mobile sensing in a complete distributed and opportunistic scheme. We present a novel sensing strategy for sensing nodes without movement constraints. This strategy offers information sharing and sensor scheduling that maximizes the bene ...

IEEE2013

Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility

Johan Auwerx, Kristina Schoonjans, Ellen Helena Jeninga

rganisms adapt their metabolism to meet ever changing environmental conditions. This metabolic adaptation involves at a cellular level the fine tuning of mitochondrial function, which is mainly under the control of the transcriptional co-activator prolifer ...

2010

From the neighbourhood to the city : resource flow modelling for urban sustainability

Jérôme Henri Kämpf, Darren Robinson, Frédéric Haldi, Diane Perez, Adil Rasheed, Urs Wilke, Philippe Leroux

Agreed intergovernmental targets to reduce the emission of greenhouse gases due to predominantly urban anthropogenic activities are becoming increasingly stringent; one might even say ambitious. One crucial strategy in achieving these targets will be to im ...

EPFL2009