Concept

Cardiomyopathie

Publications associées (25)

The role of computational methods in cardiovascular medicine: a narrative review

Alfio Quarteroni, Luca Dede', Christian Vergara, Stefano Pagani

Background and Objective: Computational models of the cardiovascular system allow for a detailed and quantitative investigation of both physiological and pathological conditions, thanks to their ability to combine clinical-possibly patient-specific-data wi ...

Ame Publishing Company2024

Development of a Transient Neural Interface for Minimally Invasive Recording and Stimulation

Adele Fanelli

Transient electronics enabling devices to safely disappear in the environment can be applied not only in green electronics, but also in bioelectronic medicine. Neural implants able to degrade harmlessly inside the body eliminate the need for removal surger ...

EPFL2022

Blood Flow to the Spleen is Altered in a Mouse Model of Spinal Muscular Atrophy

Bernard Schneider

Spinal muscular atrophy (SMA) is a neuromuscular disorder affecting young children. While pre-clinical models of SMA show small spleens, the same is not true in humans. Here, we show by doppler ultrasonography decreased splenic blood flow in Smn(2B/-) mice ...

2020

Metabolic fingerprints discriminating severity of acute ischemia using in vivo high-field H-1 magnetic resonance spectroscopy

Hongxia Lei, Lara Buscemi Estefanell

Despite the improving imaging techniques, it remains challenging to produce magnetic resonance (MR) imaging fingerprints depicting severity of acute ischemia. The aim of this study was to evaluate the potential of the overall high-field H-1 MR Spectroscopy ...

2020

An image-based computational hemodynamics study of the Systolic Anterior Motion of the mitral valve

Alfio Quarteroni, Luca Dede', Christian Vergara, Marco Fedele

Systolic Anterior Motion (SAM) of the mitral valve - often associated with Hypertrophic Obstructive Cardiomyopathy (HOCM) - is a cardiac pathology in which a functional subaortic stenosis is induced during systole by the mitral leaflets partially obstructi ...

PERGAMON-ELSEVIER SCIENCE LTD2020

Impact of aerobic exercise type on blood flow, muscle energy metabolism, and mitochondrial biogenesis in experimental lower extremity artery disease

Rolf Gruetter, Carole Poitry-Yamate

Exercise training (ET) is recommended for lower extremity artery disease (LEAD) management. However, there is still little information on the hemodynamic and metabolic adaptations by skeletal muscle with ET. We examined whether hindlimb perfusion/vasculari ...

2020

Synchrotron-based phase contrast imaging of cardiovascular tissue in mice-grating interferometry or phase propagation?

Nikolaos Stergiopoulos, Lydia Aslanidou, Bram Trachet, Goran Lovric, Mauro Ferraro, Patrick Segers

Synchrotron-based x-ray phase-contrast imaging allows for detailed 3D insight into the microstructure of soft tissue and is increasingly used to improve our understanding of mouse models of cardiovascular disease. Two techniques dominate the field: grating ...

2019

Concealed abnormal atrial phenotype in patients with Brugada syndrome and no history of atrial fibrillation

Jean-Marc Vesin, Adrian Luca, Sasan Yazdani, Lukas Kappenberger

Objectives The electrocardiogram (ECG) of patients with BrS in sinus rhythm might reflect intrinsic atrial electrical abnormalities independent from any previous atrial fibrillation (AF). Aim of this study is to investigate the presence of P-wave abnormali ...

Elsevier2018

Hierarchical Cardiac-Rhythm Classification Based on Electrocardiogram Morphology

David Atienza Alonso, Amir Aminifar, Elisabetta De Giovanni, Dionisije Sopic

Atrial Fibrillation (AF) is a type of cardiac arrhythmia that significantly increases the risk of stroke and heart failure. In general, in the case of patients affected by AF, their electrocardiogram (ECG) shows a typical pattern of irregular RR intervals ...

2017

Method for detecting abnormalities in an electrocardiogram

David Atienza Alonso, Giovanni Ansaloni, Francisco Javier Rincon Vallejos, Ruben Braojos Lopez, Srinivasan Murali

A method for classification of ECG beats into normal and different categories of abnormal beats. The method comprises the following steps, performed on a computing platform: a. performing a training phase comprising taking as an input one or more ECG beats ...

2015

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