In neuroanatomy, the precuneus is the portion of the superior parietal lobule on the medial surface of each brain hemisphere. It is located in front of the cuneus (the upper portion of the occipital lobe). The precuneus is bounded in front by the marginal branch of the cingulate sulcus, at the rear by the parieto-occipital sulcus, and underneath by the subparietal sulcus. It is involved with episodic memory, visuospatial processing, reflections upon self, and aspects of consciousness. The location of the precuneus makes it difficult to study. Furthermore, it is rarely subject to isolated injury due to strokes, or trauma such as gunshot wounds. This has resulted in it being "one of the less accurately mapped areas of the whole cortical surface". While originally described as homogeneous by Korbinian Brodmann, it is now appreciated to contain three subdivisions. It is also known after Achille-Louis Foville as the quadrate lobule of Foville. The Latin form of praecuneus was first used in 1868 and the English precuneus in 1879. The precuneus is located on the inside between the two cerebral hemispheres in the rear region between the somatosensory cortex and forward of the cuneus (which contains the visual cortex). It is above the posterior cingulate. Following Korbinian Brodmann it has traditionally been considered a homogeneous structure and with limited distinction between it and the neighboring posterior cingulate area. Brodmann mapped it as the medial continuation of lateral parietal area 7. Axon tracing research on macaque monkeys has established that it consists of three subdivisions which now have been confirmed by fMRI upon resting-state functional connectivity to also exist in humans (parallel fMRI research has also been done upon monkeys). Sensorimotor Anterior Region This occurs around the margin of the cingulate sulcus (blue in figure) and is connected with sensorimotor areas of the cerebral cortex such as the paracentral lobule, supplementary motor area, premotor cortex, somatosensory area (Brodmann area 2), parietal operculum and insula.
Valerio Zerbi, Joanes Grandjean
Henry Markram, Kathryn Hess Bellwald, Lida Kanari, Alexis Arnaudon, Ying Shi, Jay Coggan, Natali Barros Zulaica, Idan Segev, Ruth Benavides Piccione
Olaf Blanke, Lukas Heydrich, Eva Blondiaux