Concept

Homo

Publications associées (28)

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. We aim ...

Nature Portfolio2024

Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors

Konstantin Popadin

The hypothesis that the evolution of humans involves hybridization between diverged species has been actively debated in recent years. We present the following novel evidence in support of this hypothesis: the analysis of nuclear pseudogenes of mtDNA ("NUM ...

MDPI2022

The Role of Conserved Residues in the DEDDh Motif: the Proton-Transfer Mechanism of HIV-1 RNase H

RNase H is a prototypical example for two-metalion catalysis in enzymes. An RNase H activity cleaving the ribonucleic acid (RNA) backbone of a DNA/RNA hybrid is present not only in important drug targets, such as the HIV-1 reverse transcriptase, but also i ...

2021

Le fabuleux chantier: Rendre l’intelligence artificielle robustement bénéfique

El Mahdi El Mhamdi, Le Nguyen Hoang

L'histoire de nos civilisations est marquée par l'externalisation progressive de l'information, de l'invention du langage à celle de l'imprimerie. La révolution algorithmique est sans doute la plus spectaculaire de ces externalisations, car elle est incarn ...

EDP Sciences2019

2-D assembly of supramolecular nanoarchitectures on Mg(0001)

Klaus Kern, Magalí Alejandra Lingenfelder, Fernando Pablo Cometto, Bart Willem Stel, Daniel Eduardo Hurtado Salinas

In this work, a Mg(0001) single crystal is used as a novel template to grow 2D supramolecular nano-architectures. By using scanning tunnelling microscopy (STM) and high-resolution X-ray photoemission spectroscopy (HR-XPS), the formation of either a homo-mo ...

ROYAL SOC CHEMISTRY2019

Electrochemical potential window of battery electrolytes: the HOMO-LUMO misconception

Hubert Girault, Pekka Eero Peljo

A widespread misconception in the lithium ion battery literature is the equality of the energy difference of HOMO and LUMO of the solvent with the electrochemical stability window. HOMO and LUMO are concepts derived from approximated electronic structure t ...

2018

GenMon-CH : a Web-GIS application for the monitoring of Farm Animal Genetic Resources (FAnGR) in Switzerland

Stéphane Joost

Since the initation of the Global plan of action for Farm Animal Genetic Resources (FAnGR) in 2007, individual member countries, including Switzerland, should have started a monitoring program. In this context, we developed GenMon-CH, funded by the Federal ...

2017

In vivo neurochemistry of the ventral striatum and social competition in Homo sapiens

Alina Veronika Irene Strasser

Ventral striatal function and trait anxiety have been shown to influence reward-seeking behaviour and social competition in humans. Moreover, social status perceptions have been shown to modulate ventral striatal function. The neurochemical underpinnings o ...

EPFL2017

A WebGIS platform for the monitoring of Farm Animal Genetic Resources (GENMON)

Stéphane Joost, Giona Matasci, Ivo Widmer

Background In 2007, the Food and Agriculture Organization of the United Nations (FAO) initiated the Global plan of action for Farm Animal Genetic Resources (FAnGR). The main goal of this plan is to reduce further loss of genetic diversity in farm animals, ...

Public Library of Science2017

2-homopiperazine-1-yl-4h-1,3-benzothiazine-4-one derivatives and process for the preparation of 2- (homo)piperazine 1,3-benzothiazine-4-one hydrochlorides

2-homopiperazine-1-yl-4H-l, 3 -bensothiazine-4-one derivatives of formula (I) are provided. They are useful in the treatment of bacterial infections, in particular tuberculosis, buruli ulcer and leprosy. A process for the preparation of 2- (homo)piperazine ...

2016

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