Concept

Hypovolémie

Publications associées (32)

Algorithms for fluid-structure interaction problems arising in hemodynamics

We discuss in this thesis the numerical approximation of fluid-structure interaction (FSI) problems with a particular concern (albeit not exclusive) on hemodynamics applications. Firstly, we model the blood as an incompressible fluid and the artery wall as ...

EPFL2009

Diffusion of Single Molecules in Nanochannels

Philippe Renaud, Theo Lasser, Arnaud Bertsch, Nicolas Durand, Claudio Dellagiacoma, Raphaël Goetschmann

With fluorescence correlation spectroscopy (FCS), the diffusion and concentration of proteins (wheat germ agglutinin) in a nanofluidic system are measured on a single molecule level. By increasing the ionic concentration, the Debye length of the electrical ...

2009

Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus

Matteo Dal Peraro

The M2 protein of the influenza A virus is activated by low endosomal pH and performs the essential function of proton transfer into the viral interior. The resulting decrease in pH within the virion is essential for the uncoating and further replication o ...

2009

Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI

Giulio Gambarota

To enhance the success rate of antiangiogenic therapies in the clinic, it is crucial to identify parameters for tumour angiogenesis that can predict response to these therapies. In brain tumours, one such parameter is vascular leakage, which is a response ...

Nature Publishing Group2008

Full-Field Laser-Doppler Imaging and Its Physiological Significance for Tissue Blood Perfusion

Dimitri Nestor Alice Van De Ville

Using Monte Carlo simulations for a semi-infinite medium representing a skeletal muscle tissue, it is demonstrated that the zero- and first-order moments of the power spectrum for a representative pixel of a full-field laser-Doppler imager behave different ...

IOP2008

Implantable glucose sensor

For more than thirty years there has been a high demand for glucose measuring devices to replace the finger pricking methods and to improve the life quality of diabetics. Three approaches are possible, electrochemical, electromagnetic (including optical), ...

EPFL2007

Multiple glycerol shocks increase the calcium phosphate transfection of non-synchronized CHO cells

Florian Maria Wurm, David Hacker, Martin Bertschinger, Frédéric Grosjean

The exposure of CHO DG44 cells to an osmotic shock, after DNA uptake, results in a cellular volume decrease of approx. 55%. Repetitive osmotic shocks targeted different sub-populations of cells as was demonstrated using two different fluorescent reporter g ...

2006

Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia

Patrick Aebischer, Bernard Schneider

BACKGROUND: Existing animal models of anemia inadequately reflect the hematocrit usually present in chronic renal failure (CRF) patients and do not permit long-term treatment studies. The transgenic mouse strain 134.3LC (Epo-TAg(H)) displays a severe chron ...

2002

Nonuniversal velocity fluctuations of sedimenting particles

Suliana Manley

An overview is given on the experimental evidence suggesting that the magnitude of the initial fluctuations increases with cell size. For sufficiently thick cells, the magnitude is also shown to decrease over the entire time of the experiment, so that a st ...

2002

Mechanics of interstitial-lymphatic fluid transport: theoretical foundation and experimental validation

Melody Swartz

Interstitial fluid movement is intrinsically linked to lymphatic drainage. However, their relationship is poorly understood, and associated pathologies are mostly untreatable. In this work we test the hypothesis that bulk tissue fluid movement can be evalu ...

1999

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