Publications associées à Endosome

Following endocytosis, ubiquitinated signaling receptors are incorporated within intraluminal vesicles of forming multivesicular endosomes. These vesicles then follow the pathway from early to late endosomes, remaining within the endosomal lumen, and are e ...

2006

Mechanisms of pathogen entry through the endosomal compartments

Françoise Gisou van der Goot Grunberg

Several pathogens - bacteria, viruses and parasites - must enter mammalian cells for survival, replication and immune-system evasion. These pathogens generally make use of existing cellular pathways that are designed for nutrient uptake, receptor downregul ...

2006

Visualizing odorant receptor trafficking in living cells down to the single-molecule level

Horst Vogel, Horst Pick, Jean-Manuel Segura, Valérie Jacquier

Despite the importance of trafficking for regulating G protein-coupled receptor signaling, for many members of the seven transmembrane helix protein family, such as odorant receptors, little is known about this process in live cells. Here, the complete lif ...

2006

Intracellular trafficking of interleukin-1 receptor I requires Tollip

Harald Hirling, Etienne Meylan, Michel Kropf

Interleukin-1 receptor (IL-1RI) is a master regulator of inflammation and innate immunity. When triggered by IL-1beta, IL-1RI aggregates with IL-1R-associated protein (IL-1RAcP) and forms a membrane proximal signalosome that potently activates downstream s ...

Elsevier2006

Anthrax toxin: the long and winding road that leads to the kill

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

The past five years have led to a tremendous increase in our molecular understanding of the mode of action of the anthrax toxin, one of the two main virulence factors produced by Bacillus anthracis. The structures of each of the three components of the tox ...

Elsevier2005

Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters

Steinunn Baekkeskov Hanahan

The GABA-synthesizing enzyme GAD65 is synthesized as a soluble cytosolic protein but undergoes post-translational modification(s) to become anchored to the cytosolic face of Golgi membranes before targeting to synaptic vesicle membranes in neuroendocrine c ...

Company of Biologists2004

Differential sorting and fate of endocytosed GPI-anchored proteins

Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami

In this paper, we studied the fate of endocytosed glycosylphosphatidyl inositol anchored proteins (GPI- APs) in mammalian cells, using aerolysin, a bacterial toxin that binds to the GPI anchor, as a probe. We find that GPI-APs are transported down the endo ...

2002

Oiling the wheels of the endocytic pathway

Françoise Gisou van der Goot Grunberg

An ever more complete picture of the organization and function of the endocytic pathway is emerging. New mechanisms, and in particular lipid- based mechanisms that couple membrane dynamics and sorting, are being unraveled. But the final picture is still co ...

2002

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Endosome

Intra-endosomal membrane traffic

Mechanisms of pathogen entry through the endosomal compartments

Visualizing odorant receptor trafficking in living cells down to the single-molecule level

Intracellular trafficking of interleukin-1 receptor I requires Tollip

Anthrax toxin: the long and winding road that leads to the kill

ARF1 regulates Nef-induced CD4 degradation

Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters

Membrane trafficking in neurons regulated by new syntaxin 13-interacting proteins

Differential sorting and fate of endocytosed GPI-anchored proteins

Oiling the wheels of the endocytic pathway

Graph Chatbot

Chattez avec Graph Search

ARF1 regulates Nef-induced CD4 degradation

Intra-endosomal membrane traffic

Intracellular trafficking of interleukin-1 receptor I requires Tollip

Mechanisms of pathogen entry through the endosomal compartments

Visualizing odorant receptor trafficking in living cells down to the single-molecule level

Anthrax toxin: the long and winding road that leads to the kill

Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters

Differential sorting and fate of endocytosed GPI-anchored proteins

Oiling the wheels of the endocytic pathway

Membrane trafficking in neurons regulated by new syntaxin 13-interacting proteins