Publications associées à Consentement libre et éclairé

Promoting a city-river balance within neighborhoods in transition along the Rhone

Martine Laprise, Sara Sonia Formery Regazzoni, Emmanuel Rey

Relationships between cities and their waters have always been evolving. In a context of transition towards sustainability, finding a balance between the urban and river spaces may contribute to the development of new resilient neighborhoods. To that end, ...

2023

Explainability as fig leaf? An exploration of experts’ ethical expectations towards machine learning in psychiatry

The increasing implementation of programs supported by machine learning in medical contexts will affect psychiatry. It is crucial to accompany this development with careful ethical considerations informed by empirical research involving experts from the fi ...

2023

Modeling tumor size dynamics based on real-world electronic health records and image data in advanced melanoma patients receiving immunotherapy

Olivier Michielin, Federico Amato, Monia Guidi, Nadia Terranova, Daniel Abler, Alexandre Wicky

The development of immune checkpoint inhibitors (ICIs) has revolutionized cancer therapy but only a fraction of patients benefits from this therapy. Model-informed drug development can be used to assess prognostic and predictive clinical factors or biomark ...

2023

Clinical feasibility and validation of the accelerated T2 mapping sequence GRAPPATINI in brain imaging

Tom Hilbert

Rationale and objectives: To prospectively evaluate feasibility and robustness of an accelerated T2 mapping sequence (GRAPPATINI) in brain imaging and to assess its synthetic T2-weighted images (sT2w) in comparison with a standard T2-weighted sequence (T2 ...

CELL PRESS2023

Health data privacy through homomorphic encryption and distributed ledger computing: an ethical-legal qualitative expert assessment study

Marcello Ienca

Background: Increasingly, hospitals and research institutes are developing technical solutions for sharing patient data in a privacy preserving manner. Two of these technical solutions are homomorphic encryption and distributed ledger technology. Homomorph ...

BMC2022

The Role of the Composite Floor System and Framing Action in the Seismic Performance of Composite Steel Moment-Resisting Frames

Hammad El Jisr

With the advent of performance-based earthquake engineering (PBEE), the need for reliable prediction of earthquake-induced collapse of structures is essential. Despite the significant progress that has been made towards this goal, there are several hurdles ...

EPFL2022

Modeling infectious disease dynamics towards informed public health interventions, with applications on COVID-19 and cholera

Joseph Chadi Benoit Lemaitre

Emerging and existing infectious diseases pose a constant threat to individuals and communities across the world. In many cases, the burden of these diseases is preventable through public health interventions. However, taking the right decisions and design ...

EPFL2021

GA4GH: International policies and standards for data sharing across genomic research and healthcare

Jean-Pierre Hubaux, Jamal Nasir, Junjun Zhang

The Global Alliance for Genomics and Health (GA4GH) aims to accelerate biomedical advances by enabling the responsible sharing of clinical and genomic data through both harmonized data aggregation and federated approaches. The decreasing cost of genomic se ...

Elsevier2021

MP2RAGE and Susceptibility-Weighted Imaging in Lesional Epilepsy at 7T

Lijing Xin, João Pedro Forjaco Jorge, Maxime Olivier Baud, François Lazeyras, Giannina Rita Iannotti

BACKGROUND AND PURPOSE: Surgery is the first choice therapeutic approach in case of drug-resistant epilepsy. Unfortunately, up to 43% of patients referred for presurgical assessment do not have a lesion detectable by routine 3T magnetic resonance imaging ( ...

2018

Do Firms Know the Scope of their R&D Network? An Empirical Investigation of the Determinants of Network Awareness on French Survey Data

Stéphane Lhuillery

Although research and development (R&D) networks influence the innovation performance of their members, firms may not be fully aware of the scope of their network. In particular, due to cost reasons, they may not be fully informed of their “indirect ties”, ...

Taylor & Francis2011