Concept
Complexe pyruvate déshydrogénase
Publications associées (36)
Metal reduction and sporulation in Desulfotomaculum reducens
The genera Desulfotomaculum and Clostridium, belonging to the phylum Firmicutes, comprise Gram-positive, low G+C genomic content, anaerobic, spore- forming bacteria. Desulfotomaculum is a metabolically and environmentally versatile genus capable of growing ...
EPFL2014Computational, Structural, and Kinetic Evidence That Vibrio vulnificus FrsA Is Not a Cofactor-Independent Pyruvate Decarboxylase
Ursula Röthlisberger, Elizabeth Claire Brunk
The fermentation-respiration switch (FrsA) protein in Vibrio vulnificus was recently reported to catalyze the cofactor-independent decarboxylation of pyruvate. We now report quantum mechanical/molecular mechenical calculations that examine the energetics o ...
Amer Chemical Soc2013In vivo metabolic studies in skeletal and cardiac muscle using ¹³C magnetic resonance spectroscopy
Josefina Adriana Maria Bastiaansen
Cardiac and skeletal muscle function relies on a continuous energy production via fatty acid metabolism and mitochondrial oxidation of pyruvate, with a fine balance between substrate delivery and utilization. Changes in metabolism are increasingly being im ...
EPFL2013Self-priming determines high type I IFN production by plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) are responsible for the robust and immediate production of type I IFNs during viral infection. pDCs employ TLR7 and TLR9 to detect RNA and CpG motifs present in microbial genomes. CpG-A was the first synthetic stimulus a ...
2013