Dorsal column nuclei

In neuroanatomy, the dorsal column nuclei are a pair of nuclei in the dorsal columns in the brainstem. The name refers collectively to the cuneate nucleus and gracile nucleus, which are situated at the lower end of the medulla oblongata. Both nuclei contain second-order neurons of the dorsal column–medial lemniscus pathway, which convey fine touch and proprioceptive information from the body to the brain. The dorsal column nuclei project to the thalamus. The dorsal column nuclei each have an associated nerve tract in the spinal cord, the gracile fasciculus and the cuneate fasciculus. Both dorsal column nuclei contain synapses from afferent nerve fibers that have travelled in the spinal cord. They then send on second-order neurons of the dorsal column–medial lemniscal pathway. Neurons of the dorsal column nuclei eventually reach the midbrain and the thalamus. They send axons that form the internal arcuate fibers. These cross over at the sensory decussation to form the medial lemniscus. They then synapse with third-order neurons of the thalamus. The major nuclei are the cuneate nucleus and gracile nucleus. These are present at the bottom of the medulla oblongata. The gracile nucleus is medial to the cuneate nucleus. Its neurons receive afferent input from dorsal root ganglia sensory neurons of the lower torso and the lower limbs. The gracile nucleus and gracile fasciculus carry epicritic, kinesthetic, and conscious proprioceptive information from the lower part of the body (below the level of T6 in the spinal cord). Because of the large population of neurons in the gracile nucleus they give rise to a raised area called the gracile tubercle on the posterior side of the closed medulla at the floor of the fourth ventricle. The cuneate nucleus is lateral to the gracile nucleus. It carries the same type of information, but from the upper body and the upper limbs (except the face, which is carried by the principal sensory nucleus of trigeminal nerve). The cuneate nucleus is wedge-shaped and located in the closed part of the medulla.

Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights

Task-driven neural network models predict neural dynamics of proprioception: Experimental data, activations and predictions of neural network models

Task-driven neural network models predict neural dynamics of proprioception

Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights

Task-driven neural network models predict neural dynamics of proprioception

Task-driven neural network models predict neural dynamics of proprioception: Experimental data, activations and predictions of neural network models