Concept

Mémoire sémantique

Publications associées (215)

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Nectins are cell adhesion molecules that are widely expressed in the brain. Nectin expression shows a dynamic spatiotemporal regulation, playing a role in neural migratory processes during development. Nectin-1 and nectin-3 and their heterophilic trans-int ...

Public Library of Science2013

Dynamic reconfiguration of human brain functional networks through neurofeedback

Dimitri Nestor Alice Van De Ville, Frank Scharnowski, Rotem Roza Kopel

Recent fMRI studies demonstrated that functional connectivity is altered following cognitive tasks (e.g., learning) or due to various neurological disorders. We tested whether real-time fMRI-based neurofeedback can be a tool to voluntarily reconfigure brai ...

Elsevier2013

Age-related cognitive impairments in mice with a conditional ablation of the neural cell adhesion molecule

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Most of the mechanisms involved in neural plasticity support cognition, and aging has a considerable effect on some of these processes. The neural cell adhesion molecule (NCAM) of the immunoglobulin superfamily plays a pivotal role in structural and functi ...

Cold Spring Harbor Lab Press, Publications Dept2013

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

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PC7 belongs to the proprotein convertase family, whose members are implicated in the cleavage of secretory precursors. The in vivo function of PC7 is unknown. Herein, we find that the precursor proBDNF is processed into mature BDNF in COS-1 cells coexpress ...

National Academy of Sciences2013

Increased axonal bouton dynamics in the aging mouse cortex

Graham Knott, Bohumil Maco, Ge Gao

Aging is a major risk factor for many neurological diseases and is associated with mild cognitive decline. Previous studies suggest that aging is accompanied by reduced synapse number and synaptic plasticity in specific brain regions. However, most studies ...

National Academy of Sciences2013

Acute Caffeine Administration Impact On Working Memory-Related Brain Activation And Functional Connectivity In The Elderly: A Bold And Perfusion Mri Study

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In young individuals, caffeine-mediated blockade of adenosine receptors and vasoconstriction has direct repercussions on task-related activations, changes in functional connectivity, as well as global vascular effects. To date, no study has explored the ef ...

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Iterative Learning and Denoising in Convolutional Neural Associative Memories

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The task of a neural associative memory is to retrieve a set of previously memorized pat- terns from their noisy versions by using a net- work of neurons. Hence, an ideal network should be able to 1) gradually learn a set of patterns, 2) retrieve the corre ...

2013

Histone acetylation: molecular mnemonics on the chromatin

Johannes Gräff

Long-lasting memories require specific gene expression programmes that are, in part, orchestrated by epigenetic mechanisms. Of the epigenetic modifications identified in cognitive processes, histone acetylation has spurred considerable interest. Whereas in ...

2013

Two brakes are better than one: the neural bases of inhibitory control of motor memory traces

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Inhibitory control of actions is one important aspect in daily life to warrant adequate context related behavior. Alpha activity (oscillatory brain activity around 10Hz) has been suggested to play a major role for the implementation of inhibitory control. ...

Elsevier2013

Auditory perceptual decision-making based on semantic categorization of environmental sounds

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Discriminating complex sounds relies on multiple stages of differential brain activity. The specific roles of these stages and their links to perception were the focus of the present study. We presented 250 ms duration sounds of living and man-made objects ...

2012

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