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A fundamental goal of population genetics is to determine and quantify the interplay of mutation, natural selection, genetic drift and migration in shaping allelic frequency changes that underpin evolution-ary change. In this dissertation, I present comput ...
Lande and Arnold's approach to quantifying natural selection has become a standard tool in evolutionary biology due to its simplicity and generality. It treats linear and nonlinear selection in two separate frameworks, generating coefficients of selection ...
Symmetry-breaking transitions associated with the buckling and folding of curved multilayered surfaces—which are common to a wide range of systems and processes such as embryogenesis, tissue differentiation and structure formation in heterogeneous thin fil ...
The uptake of glutamate by synaptic vesicles is mediated by vesicular glutamate transporters (VGLUTs). The central role of these transporters in excitatory neurotransmission underpins their importance as pharmacological targets. Although several compounds ...
Understanding the extent to which humans perceive the emotional state of animals has both theoretical and practical implications. While recent studies indicate that natural selection has led to some convergence of emotion coding among vertebrate species (i ...
Recent experiments indicate that static stripe-like charge order is generic to the hole-doped copper oxide superconductors and competes with superconductivity. Here we show that a similar type of charge order is present in La-5/Sr-3(1)/3CoO4, an insulating ...
Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The p ...
Complex cognition and relatively large brains are distributed across various taxa, and many primarily verbal hypotheses exist to explain such diversity. Yet, mathematical approaches formalizing verbal hypotheses would help deepen the understanding of brain ...
Circadian rhythms are oscillations in behavior, metabolism and physiology that have a period close to 24 h. These rhythms are controlled by an internal pacemaker that evolved under strong selective pressures imposed by environmental cyclical changes, mainl ...
Humans like some colours and dislike others, but which particular colours and why remains to be understood. Empirical studies on colour preferences generally targeted most preferred colours, but rarely least preferred (disliked) colours. In addition, findi ...