Concept

Hippocampe (cerveau)

Publications associées (246)

Stress suppresses and learning induces plasticity in CA3 of rat hippocampus: a three-dimensional ultrastructural study of thorny excrescences and their postsynaptic densities

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

Chronic stress and spatial training have been proposed to affect hippocampal structure and function in opposite ways. Previous morphological studies that addressed structural changes after chronic restraint stress and spatial training were based on two-dim ...

2005

Microcircuits in action--from CPGs to neocortex

Henry Markram, Gilad Silberberg

To understand the interface between global brain function and molecular neuroscience--that is, the microcircuit level--a major challenge. Such understanding is prerequisite if we are to account for neural function in cellular terms. Very few vertebrate mic ...

2005

In vivo effect of chronic hypoxia on the neurochemical profile of the developing rat hippocampus

Rolf Gruetter

The cognitive deficits observed in children with cyanotic congenital heart disease suggest involvement of the developing hippocampus. Chronic postnatal hypoxia present during infancy in these children may play a role in these impairments. To understand the ...

Elsevier2005

Modelling Path Integrator Recalibration Using Hippocampal Place cells

Wulfram Gerstner, Ricardo Andres Chavarriaga Lozano, Thomas Strösslin

The firing activities of place cells in the rat hippocampus exhibit strong correlations to the animal's location. External (e.g. visual) as well as internal (proprioceptive and vestibular) sensory information take part in controlling hippocampal place fiel ...

Springer-Verlag GmbH2005

Metabolic activation pattern of distinct hippocampal subregions during spatial learning and memory retrieval

Pierre Magistretti, Luc Pellerin

Activation dynamics of hippocampal subregions during spatial learning and their interplay with neocortical regions is an important dimension in the understanding of hippocampal function. Using the (14C)-2-deoxyglucose autoradiographic method, we have chara ...

2005

Robust self-localisation and navigation based on hippocampal place cells

Wulfram Gerstner, Ricardo Andres Chavarriaga Lozano, Thomas Strösslin

A computational model of the hippocampal function in spatial learning is presented. A spatial representation is incrementally acquired during exploration. Visual and self-motion information is fed into a network of rate-coded neurons. A consistent and stab ...

Elsevier2005

Selective postsynaptic co-localization of MCT2 with AMPA receptor GluR2/3 subunits at excitatory synapses exhibiting AMPA receptor trafficking

Pierre Magistretti, Luc Pellerin

MCT2 is the main neuronal monocarboxylate transporter needed by neurons if they are to use lactate as an additional energy substrate. Previous evidence suggested that some MCT2 could be located in postsynaptic elements of glutamatergic synapses. Using post ...

2005

Spatial learning and navigation in the rat

Ricardo Andres Chavarriaga Lozano

Animals behave in different ways depending on the specific task they are required to solve. In certain cases, if a cue marks the goal location, they can rely on simple stimulusresponse associations. In contrast, other tasks require the animal to be endowed ...

EPFL2005

Subthreshold cross-correlations between cortical neurons: A reference model with static synapses

Wulfram Gerstner, Henry Markram, Gilad Silberberg

The structure of cross-correlations between subthreshold potentials of neocortical neurons was recently examined. Characteristic features included broad widths and significant peak advances. It was suggested that dynamic synapses shape these cross-correlat ...

Elsevier2005

Short-term-plasticity orchestrates the response of pyramidal cells and interneurons to population bursts

Wulfram Gerstner, Henry Markram, Gilad Silberberg

The synaptic drive from neuronal populations varies considerably over short time scales. Such changes in the presynaptic rate trigger many temporal processes absent under steady-state conditions. This paper examines the differential impact of pyramidal cel ...

2005

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