Concept

Diagnostic préimplantatoire

Publications associées (98)

Molecular Criteria for Defining the Naive Human Pluripotent State

Didier Trono, Evaristo Jose Planet Letschert, Julien Léonard Duc, Marc Samuel Friedli, Alexandra Iouranova, Michaël Imbeault, Julien Paul André Pontis, Haoyi Wang

Recent studies have aimed to convert cultured human pluripotent cells to a naive state, but it remains unclear to what extent the resulting cells recapitulate in vivo naive pluripotency. Here we propose a set of molecular criteria for evaluating the naive ...

Cell Press2016

Performance degradation diagnosis of thermal power plants: A method based on advanced exergy analysis

Ligang Wang

The performance of energy systems usually degrades gradually away from the best operation conditions during continuous operation. Since the components in an energy system are interconnected with each other, the performance degradation or anomalies occurrin ...

2016

Versatile size-dependent sorting of C-elegans nematodes and embryos using a tunable microfluidic filter structure

Martinus Gijs, Thomas Lehnert, Matteo Cornaglia, Li Dong

The roundworm Caenorhabditis elegans (C. elegans) is a powerful model organism for addressing fundamental biological questions related to human disease and aging. Its life cycle consists of an embryo stage, four larval stages that can be clearly distinguis ...

Royal Soc Chemistry2016

Cognitive markers as potential endophenotypes for schizophrenia

Michael Herzog, Maya Roinishvili

Schizophrenia is a heterogeneous disease strongly influenced by genetic predisposition. A large variety of candidate genes has been identified of which each gene, however, explains only a small proportion of the genetic risk. For this reason, stable marker ...

2016

Segmentation of Developing Human Embryo in Time-lapse Microscopy

Mathieu Salzmann

Being able to efficiently segment a developing embryo from background clutter constitutes an important step in automated monitoring of human embryonic cells. State-of-the-art automatic segmentation methods remain ill-suited to handle the complex behavior a ...

IEEE2016

Mass Barcode Signal Amplification for Multiplex Allergy Diagnosis by MALDI-MS

Hubert Girault, Natalia Gasilova, Liang Qiao, Xiaoqin Zhong

A highly sensitive method based on mass-barcoded gold nanoparticles (AuNPs) and immunomagnetic separation has been developed for multiplex allergy diagnosis by MALDI mass spectrometry in a component-resolved manner. Different analytical probes were prepare ...

American Chemical Society2016

Privacy Threats and Practical Solutions for Genetic Risk Tests

Jean-Pierre Hubaux, Erman Ayday, Jean Louis Raisaro, Ludovic Barman, Mohammed-Taha El Graini

Recently, several solutions have been proposed to address the complex challenge of protecting individuals’ genetic data during personalized medicine tests. In this short paper, we analyze different privacy threats and propose simple countermeasures for the ...

2015

Epigenetic Alterations in Alzheimer's Disease

Johannes Gräff, Jose Vicente Sanchez Mut

Alzheimer's disease (AD) is the major cause of dementia in Western societies. It progresses asymptomatically during decades before being belatedly diagnosed when therapeutic strategies have become unviable. Although several genetic alterations have been as ...

Frontiers Research Foundation2015

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages

Didier Trono, Anna Claire Groner

Mammalian development begins with the segregation of embryonic and extra-embryonic lineages in the blastocyst. Recent studies revealed cell-to-cell gene expression heterogeneity and dynamic cell rearrangements during mouse blastocyst formation. Thus, mecha ...

2015

Hydraulic transients in straight and coil pipe rigs

Anton Schleiss, Pedro Filipe De Almeida Manso, David Ferràs Segura

Transient pressure waves in real pipe systems are affected by several phenomena not accounted for in the classic waterhammer theory. Damping mechanisms are differently manifested according to the material, configuration and existing features of pipe system ...

2015

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