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Marginal structural models (MSMs) allow for causal analysis of longitudinal data. The standard MSM is based on discrete time models, but the continuous-time MSM is a conceptually appealing alternative for survival analysis. In applied analyses, it is often ...
A directed acyclic graph (DAG) is the most common graphical model for representing causal relationships among a set of variables. When restricted to using only observational data, the structure of the ground truth DAG is identifiable only up to Markov equi ...
In causal inference the effect of confounding may be controlled using regression adjustment in an outcome model, propensity score adjustment, inverse probability of treatment weighting or a combination of these. Approaches based on modelling the treatment ...
The relationship between collapsibility and confounding has been subject to an extensive and ongoing discussion in the methodological literature. We discuss two subtly different definitions of collapsibility, and show that by considering causal effect meas ...
The role of randomness, environment and genetics in cancer development is debated. We approach the discussion by using the potential outcomes framework for causal inference. By briefly considering the underlying assumptions, we suggest that the antagonisin ...
Counter-intuitive associations appear frequently in epidemiology, and these results are often debated. In particular, several scenarios are characterized by a general risk factor that appears protective in particular subpopulations, for example, individual ...
Coal burning power plants are a frequent target of regulatory programmes because of their emission of chemicals that are known precursors to the formation of ambient particulate air pollution. Health impact assessments of emissions from coal power plants t ...
The participants in randomized trials and other studies used for causal inference are often not representative of the populations seen by clinical decision-makers. To account for differences between populations, researchers may consider standardizing resul ...
It has been nearly 10 years since Ghazanfar and Schroeder (2006) proposed that the neocortex is essentially multisensory in nature. However, it is only recently that sufficient and hard evidence that supports this proposal has accrued. We review evidence t ...
The concept of causality is naturally related to processes developing over time. Central ideas of causal inference like time-dependent confounding (feedback) and mediation should be viewed as dynamic concepts. We shall study these concepts in the context o ...