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Bicyclic peptide ligands are promising molecules for the development of new therapeutics. They combine advantages from large protein therapeutics and small molecule drugs. Large combinatorial libraries of bicyclic peptides can be generated and screened by ...
Working in the context of symmetric spectra, we describe and study a homotopy completion tower for algebras and left modules over operads in the category of modules over a commutative ring spectrum (eg structured ring spectra). We prove a strong convergenc ...
Let M be a monoidal category endowed with a distinguished class of weak equivalences and with appropriately compatible classifying bundles for monoids and comonoids. We define and study homotopy-invariant notions of normality for maps of monoids and of con ...
We study classes of modules over a commutative ring which allow to do homological algebra relative to such a class. We classify those classes consisting of injective modules by certain subsets of ideals. When the ring is Noetherian the subsets are precisel ...
The concept of isogeometric analysis (IGA) was first applied to the approximation of Maxwell equations in [A. Buffa, G. Sangalli, and R. Vázquez, Comput. Methods Appl. Mech. Engrg., 199 (2010), pp. 1143-1152]. The method is based on the construction of sui ...
Let G be a finite group and let R be a commutative ring. We analyse the (G,G)-bisets which stabilize an indecomposable RG-module. We prove that the minimal ones are unique up to equivalence. This result has the same flavor as the uniqueness of vertices and ...
Avoiding the formation of rings in rotary kilns is an issue of primary concern to the cement production industry. We developed a numerical combustion model that revealed that in our case study rings are typically formed in zones of maximal radiative heat t ...
Phage selections with combinatorial libraries of uniformly sized bicyclic peptides have recently yielded potent and selective binders of several protein targets. In this work we varied in a combinatorial fashion the ring sizes of bicyclic peptides in phage ...
The low-temperature adsorption of isolated transition metal adatoms (Mn, Co, and Fe) onto hexagonal boron nitride monolayers on Rh(111) creates a bistable adsorption complex. The first state considerably weakens the hexagonal boron nitride- (h-BN-) substra ...
Methods for direct data-driven tuning of the parameters of precompensators for LPV systems are developed. Since the commutativity property is not always satisfied for LPV systems, previously proposed methods for LTI systems that use this property cannot be ...